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NCT07503964: DILAILA
The Significance of Laparoscopic Transcystic Papilla Vateri Balloon Dilatation in Patients With Choledocholithiasis.
NA trial testing Endoscopic retrograde cholangiopancreatography with papillotomy and stone evacuation from common bile duct. in Choledocholithiasis in 100 participants. Participants enrolled and being followed up; not accepting new ones.
1 October 2027
Quick facts
| Lead sponsor | Riga East Clinical University Hospital |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 May 2025 |
| Primary completion | 1 October 2027 |
| Estimated completion | 1 October 2028 |
| Sites | 1 location across Latvia |
Drugs / interventions tested
- Endoscopic retrograde cholangiopancreatography with papillotomy and stone evacuation from common bile duct.
- Laparoscopic Cholecystectomy.
- Laparoscopic transcystic balloon dilatation of the papilla Vateri.
Conditions studied
- Choledocholithiasis — all drugs for Choledocholithiasis →
- Choledocholithiasis With Cholecystitis — all drugs for Choledocholithiasis With Cholecystitis →
Sponsor
Riga East Clinical University Hospital
Who can join
18 and older, any sex, with Choledocholithiasis or Choledocholithiasis With Cholecystitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A prospective randomized trial. It is planned to analyze groups of patients with cholecystitis and choledocholithiasis. As part of the study, after signing the consent, the patients will be divided into two groups that have indications for surgical therapy. A two-stage therapy will be applied to one group, where initially endoscopic retrograde cholangiopancreatography with evacuation of gallstone from the common bile duct will be prescribed, and as the second stage, patients will undergo surgery - laparoscopic cholecystectomy. For the second group, a one-stage therapy tactic will be applied, where during the operation (laparoscopic cholecystectomy), transcystic papilla Vateri balloon dilation with antegrade gallstone evacuation from the common bile duct will be applied. For patients who will be proven to have a stone in the common bile duct and patients who meet the study inclusion criteria, a sealed envelope will be placed in the medical history with a specific therapeutic tactic that will be applied to the patient's treatment. Each envelope will be assigned a number. Using a computer and a randomizer, an envelope with a number will be selected, which will be assigned to each patient. The postoperative course, duration of surgery, length of hospitalization, types of complications and their frequency after surgery, the creator of successful outcomes, the cost of the treatment method in the specific medical institution will be analyzed. The data will be processed with the IBM SPSS program and analyzed according to the parametric/non-parametric distribution of the data.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07503964
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Related trials
Other recruiting trials for Choledocholithiasis
Currently open trials in the same condition.
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- NCT07008170 — Laparoendoscopic Rendezvous for Concomitant Gall Bladder Stones and Common Bile Duct Stones · NA · recruiting
- NCT07130864 — Early vs Late Laparoscopic Cholecystectomy After Common Bile Duct Stones Clearance Through Ercp. · NA · recruiting
- NCT07407491 — Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis · Phase 2 · recruiting
- NCT06197984 — Antimicrobial Resistance in Acute Cholangitis · recruiting
Other Riga East Clinical University Hospital trials
Trials by the same sponsor.
- NCT07271862 — A Novel Laparoscopic Apical Promontofixation Technique With Simultaneous Perineal Reconstruction for Patients With Sympt · NA · active not recruiting
- NCT05592496 — Bilateral Retromuscular Rectus Sheath Block Catheters Usage for Early Postoperative Analgesia After Laparotomic Gastrect · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07503964 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Riga East Clinical University Hospital
- Last refreshed: 31 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07503964.
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