Last reviewed · How we verify
NCT06335004
Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases
trial testing Magnetic resonance imaging in Glymphatic System in 100 participants. Status unknown.
31 December 2024
Quick facts
| Lead sponsor | IRCCS Eugenio Medea |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 1 March 2022 |
| Primary completion | 31 December 2024 |
| Estimated completion | 28 February 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Magnetic resonance imaging
Conditions studied
- Glymphatic System — all drugs for Glymphatic System →
- White Matter Disease — all drugs for White Matter Disease →
- Pediatric Disorder — all drugs for Pediatric Disorder →
- Perivascular Disease — all drugs for Perivascular Disease →
Sponsor
IRCCS Eugenio Medea — full company profile →
Who can join
Adults 9 Months to 70, any sex, with Glymphatic System or White Matter Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The dilation of perivascular spaces can be the result of various etiopathogenetic processes. White matter atrophy can cause enlargement of these perivascular spaces (PVS) but also obstruction of fluid drainage systems (interstitial fluid, ISF) and metabolites, as evidenced by some recent studies. Focal stagnation of liquids and deposition of toxic material induce tissue hypoxia and neuroglial dysfunction. Dilation of PVS can be associated with changes in white matter and microhemorrhages. We want to study these etiopathogenetic phenomena by implementing specific MRI methods.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06335004
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Magnetic resonance imaging
Trials testing the same drug.
- NCT06528769 — Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma · Phase 2 · recruiting
- NCT07148167 — Comparison of Cervical Extensor Muscle Thickness, Fat Infiltration, and Cervical Alignment in Patients With Ankylosing S · completed
- NCT06432023 — Imaging - Clinical Evaluation of Altered Nervous System Drainage · recruiting
- NCT06010550 — Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo · unknown
- NCT05698563 — Intermetatarsal Bursitis in Patients With Rheumatoid Arthritis · NA · terminated
Other recruiting trials for Glymphatic System
Currently open trials in the same condition.
- NCT06950099 — Advanced Neuroimaging in Idiopathic Intracranial Hypertension · recruiting
Other IRCCS Eugenio Medea trials
Trials by the same sponsor.
- NCT07095062 — Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome. · NA · recruiting
- NCT06993389 — AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients · recruiting
- NCT06999850 — Implementation and Validation of Instrumented Stair Climb Test · NA · recruiting
- NCT06666777 — Speech Therapy and Parenting for Early Socio-communicAtive sKills · NA · recruiting
- NCT07470138 — Sleep Disturbance in Subjects With Autism Spectrum Disorders (ASD) in Preschool Age (18-60 Months) · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06335004 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS Eugenio Medea
- Last refreshed: 28 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06335004.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing