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NCT06259396
The 8x5 Diet for Bile Acid Diarrhoea: A Feasibility Randomised Controlled Trial
NA trial testing The 8x5 Diet in Bile Acid Diarrhea in 76 participants. Currently enrolling.
31 March 2025
Quick facts
| Lead sponsor | University of Manchester |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 76 |
| Start date | 2 April 2024 |
| Primary completion | 31 March 2025 |
| Estimated completion | 31 March 2025 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- The 8x5 Diet
Conditions studied
- Bile Acid Diarrhea — all drugs for Bile Acid Diarrhea →
Sponsor
University of Manchester
Who can join
18 and older, any sex, with Bile Acid Diarrhea. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Bile acid diarrhoea is a common cause of chronic watery diarrhoea. Treatment is life-long medication. However, about 50% of people have ongoing, bothersome diarrhoea. Findings from recent research on diet therapies and food intolerances have been used to develop a healthy dietary pattern called The 8x5 Diet. We will test the practicalities of conducting a randomised controlled trial of this dietary intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Diet therapy (The 8×5 Diet) for adults living with bile acid diarrhoea: protocol for a feasibility randomised controlled trial.
McKenzie YA, Kelman L, O'Connor M, Todd C, et al · · 2025 · cited 1× · PMID 40147991 · DOI 10.1136/bmjopen-2024-097973
Verify or expand the search:
- PubMed search for NCT06259396
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06259396 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Manchester
- Last refreshed: 16 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06259396.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing