Last reviewed · How we verify
NCT07381894
Multicentre Hypertrophic Cardiomyopathy Registry
trial in Hypertrophic Cardiomyopathy (HCM) in 2,500 participants. Not yet recruiting.
1 January 2029
Quick facts
| Lead sponsor | University of Manchester |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 2,500 |
| Start date | 1 February 2026 |
| Primary completion | 1 January 2029 |
| Estimated completion | 1 January 2029 |
| Sites | 1 location across United Kingdom |
Conditions studied
- Hypertrophic Cardiomyopathy (HCM) — all drugs for Hypertrophic Cardiomyopathy (HCM) →
Sponsor
University of Manchester
Who can join
Adults 18 to 99, any sex, with Hypertrophic Cardiomyopathy (HCM). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hypertrophic cardiomyopathy (HCM) is the most common inherited heart condition, affecting approximately 1 in 500 people. It causes the heart muscle to thicken, which can lead to blockages in blood flow (left ventricular outflow tract obstruction), shortness of breath, and an increased risk of heart failure or sudden cardiac arrest. While standard treatments exist and new targeted medications (cardiac myosin inhibitors) have recently been approved, doctors still need better data to predict which treatments will work best for each individual patient. This national registry based in the UK is a secure database that collects health information from HCM patients across multiple NHS hospital sites in the UK over several years. Participants in this study will have their routine health information collected from their medical records, including details from heart scans (echocardiograms and MRIs), blood tests, and genetic information. With this HCM registry, we aim to improve disease understanding and risk prediction, paving the way for more personalised treatment plans for the HCM community in the future
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07381894
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hypertrophic Cardiomyopathy (HCM)
Currently open trials in the same condition.
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- NCT07359690 — Multimodal Analysis of Endomyocardial Biopsies · recruiting
- NCT07344480 — Retrospective Natural History Study of RASopathy-associated Cardiomyopathy (RAS-CM) · recruiting
- NCT06882668 — Role of Cardiovascular Imaging in the Early Diagnosis of Hypertrophic Cardiomyopathy in Women · active not recruiting
- NCT06599229 — Perfusion Abnormalities in Hypertrophic Cardiomyopathy · active not recruiting
Other University of Manchester trials
Trials by the same sponsor.
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- NCT07084090 — Using IF-THEN Plans to Support Patients in Raising Safety Concerns About Their Care · NA · not yet recruiting
- NCT07494760 — A Feasibility Randomised Control Trial to Evaluate Early Perinatal Bereavement Counselling for Parents Who Have Experien · NA · not yet recruiting
- NCT07372885 — GRanulocyte Augmented Cord Blood Transplantation for Poor Risk leukaEmia · Phase 1, PHASE2 · not yet recruiting
- NCT07173569 — St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07381894 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Manchester
- Last refreshed: 2 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07381894.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing