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NCT06250764
Asprosin, Adropin, Irisin Levels in Periodontitis
trial testing Clinical periodontal measuremenets in Periodontal Diseases in 122 participants. Completed in 23 February 2022.
23 February 2022
Quick facts
| Lead sponsor | AYSAN LEKTEMUR ALPAN |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 122 |
| Start date | 12 February 2020 |
| Primary completion | 23 February 2022 |
| Estimated completion | 23 February 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Clinical periodontal measuremenets
- ELISA test from gingival crevicular fluid (GCF)
Conditions studied
- Periodontal Diseases — all drugs for Periodontal Diseases →
- Gingivitis — all drugs for Gingivitis →
- Obesity — all drugs for Obesity →
Sponsor
AYSAN LEKTEMUR ALPAN
Who can join
Adults 25 to 60, any sex, with Periodontal Diseases or Gingivitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The recently discovered association of the hormones 'asprosin, adropin and irisin' with obesity and metabolic status, as well as the fact that periodontal diseases are affected by obesity and nutrition bilaterally, have led us to investigate the relationship between selected target markers and periodontal disease. The primary aim and main objective of this study is to increase the knowledge and to direct future researches as a result of the lack of adequate research in the past and the very limited investigations with these hormones in dentistry and periodontology. Our study was conducted on 122 patients who applied to Adıyaman University Faculty of Dentistry and were referred to the Department of Periodontology for routine periodontal controls. Participants' gender, age, height, weight, BMI, education level, tooth brushing and flossing habits as well as clinical parameters PI, GI, SCD, CAS and SDI were noted. Participants were divided into 4 groups as healthy, gingivitis, initial periodontitis and advanced periodontitis and grouped according to the current periodontal classification of 2017. DOS was collected from the groups for examination and 'asprosin, adropin and irisin' values in the samples were evaluated by ELISA test.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06250764
- Europe PMC full search
- ASCO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06250764 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by AYSAN LEKTEMUR ALPAN
- Last refreshed: 9 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06250764.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing