NCT06247124

OPERATION WIPE OUT: Multi-Channel Communication Campaign to Promote HPV Vaccination in Chambers County, Alabama

Active, enrolled NA Last updated 9 February 2026

What this trial tests

NA trial testing multi-channel communication campaign to promote HPV vaccination in HPV Vaccination in 29 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

1 November 2023

Primary endpoint
31 March 2026

31 March 2026

Quick facts

Lead sponsor	University of Alabama at Birmingham
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	prevention
Enrollment	29
Start date	1 November 2023
Primary completion	31 March 2026
Estimated completion	31 March 2026
Sites	1 location across United States

Drugs / interventions tested

• multi-channel communication campaign to promote HPV vaccination

Conditions studied

• HPV Vaccination — all drugs for HPV Vaccination →

Sponsor

University of Alabama at Birmingham

Who can join

Adults 15 to 18, any sex, with HPV Vaccination. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Advisory Committee on Immunization Practices (ACIP) recommends HPV vaccination for all children and adults ages 9 to 26 in the U.S. However, HPV vaccination rates nationally and in Alabama lag far behind the Healthy People 2020 goal of 80% coverage. Despite multiple efforts, Alabama still ranks third in cervical cancer mortality and incidence nationally with great disparities within the state, particularly between urban and rural counties. In order to address this public health challenge, organizations have come together to develop, implement, and evaluate a statewide action plan to eliminate cervical cancer as a public health problem in Alabama by 2033. This plan was officially launched by the State Health Officer in May 2023 as a partnership between government, academia, civic organizations, and non-profit organizations and is known as OPERATION WIPE OUT. The overall goal of this Supplement is to develop, implement, and examine the feasibility and scalability of a theory-driven, participatory multi-channel communication campaign to promote HPV vaccination uptake that is designed and delivered by high school students with the support of OPERATION WIPE OUT partners and linked to school-based vaccination in a rural county that has the highest cervical cancer incidence in the state (Chambers County). The specific aims are: (1) To develop and examine the feasibility of a theory-driven, participatory multi-channel communication campaign to promote HPV vaccination uptake with high school students being agents of change and provision of school-based vaccination; and (2) To examine specific features of the multi-channel communication campaign regarding scalability, sustainability, and potentially a future full-scale implementation science trial. The primary outcome will be HPV vaccination uptake at the county level obtained Alabama Department of Public Health Vaccination Registry (ImmPRINT). Additionally, treatment fidelity and scalability assessments will be conducted to inform sustainability efforts.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.