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NCT06232278: CLAPOT
Long-term Results of Percutaneous Left Atrial Closure at Brest University Hospital (CLAPOT)
trial in Atrial Fibrillation in 120 participants. Status unknown.
31 May 2024
Quick facts
| Lead sponsor | University Hospital, Brest |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 120 |
| Start date | 1 February 2024 |
| Primary completion | 31 May 2024 |
| Estimated completion | 31 May 2025 |
| Sites | 1 location across France |
Conditions studied
- Atrial Fibrillation — all drugs for Atrial Fibrillation →
- Cardioembolic Stroke — all drugs for Cardioembolic Stroke →
- Left Atrial Appendage Thrombosis — all drugs for Left Atrial Appendage Thrombosis →
- Anticoagulant-induced Bleeding — all drugs for Anticoagulant-induced Bleeding →
Sponsor
University Hospital, Brest
Who can join
18 and older, any sex, with Atrial Fibrillation or Cardioembolic Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Atrial Fibrillation represents an important risk of cardioembolic stroke. In more than 90% of cases, thrombus originate in the left atrial appendage. Therefore guidelines recommend the anticoagulation of patients with atrial fibrillation and a significant cardioembolic risk, predicted by the CHA2DS2VASc score. However, serious bleeding complications may definitively contraindicate the use of anticoagulants. For those patients, percutaneous Left Atrial Appendage Occlusion (LAAO) has became a recommended alternative to prevent the thrombus formation and reduce the risk of cardioembolic events. In the CHU of Brest, more than 120 patients have been treated with LAAO for the last 8 years with two different occluder devices : WATCHMAN®, Boston Scientifc and AMPLATZER Amulet®, Abbott Laboratories. This retrospective longitudinal observational study named CLAPOT (CHU of Brest' Left Atrial Appendage Percutaneous Occlusion Treatment) aims to evaluate the long term results of this procedure for effectiveness and safety and to compare the results between the two devices (Watchman and Amplatzer).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06232278
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06232278 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Brest
- Last refreshed: 9 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06232278.
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