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NCT06231004
Correlation Between the Microbiome and Type 2 Inflammatory Diseases of CRSwNP
trial testing glucocorticosteroid and surgery in Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) in 1,000 participants. Not yet recruiting.
1 September 2026
Quick facts
| Lead sponsor | The First Affiliated Hospital with Nanjing Medical University |
|---|---|
| Status | Not yet recruiting |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 22 January 2024 |
| Primary completion | 1 September 2026 |
| Estimated completion | 1 September 2032 |
Drugs / interventions tested
- glucocorticosteroid and surgery
Conditions studied
- Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) — all drugs for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) →
Sponsor
The First Affiliated Hospital with Nanjing Medical University
Who can join
Adults 18 to 80, any sex, with Chronic Rhinosinusitis With Nasal Polyps (CRSwNP). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Nasal microorganisms, exfoliated cells, nasal secretions, fetal microorganisms and blood were collected from patients with chronic sinusitis with nasal polyps before medication. Nasal polyp tissues of the patients were clamped for pathologic biopsy in the outpatient clinic. Methylprednisolone was then administered to the patients for 17 days, and the nasal microbial changes were observed after the administration of the drug. Patients underwent surgical treatment after the administration of the drug, and postoperative patients were followed up for a long period of time until polyp recurrence. During the follow-up, the microorganisms in the patients' postoperative nasal cavities were collected and the postoperative microbial changes were recorded
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06231004
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Currently open trials in the same condition.
- NCT07399665 — ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia · recruiting
- NCT07125586 — Real-Time Diagnosis of Eosinophilic Nasal Polyps Using High-Sensitivity Spectroscopy · NA · recruiting
- NCT06776042 — Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery · NA · recruiting
Other The First Affiliated Hospital with Nanjing Medical University trials
Trials by the same sponsor.
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- NCT07523789 — Comparison of Chemotherapy and Immunotherapy in Neoadjuvant Therapy for TNBC · not yet recruiting
- NCT07464756 — SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer · Phase 2 · not yet recruiting
- NCT07482826 — Full-Endoscopic Decompression vs. Endoscopic Lumbar Fusion for Middle-Aged and Older Adults With Spinal Stenosis · NA · not yet recruiting
- NCT07558863 — Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06231004 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The First Affiliated Hospital with Nanjing Medical University
- Last refreshed: 30 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06231004.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing