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NCT06225895
Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
NA trial testing general anesthesia in Analgesia in 72 participants. Completed in 1 September 2024.
1 August 2024
Quick facts
| Lead sponsor | Zagazig University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 72 |
| Start date | 1 February 2024 |
| Primary completion | 1 August 2024 |
| Estimated completion | 1 September 2024 |
| Sites | 2 locations across Egypt |
Drugs / interventions tested
- general anesthesia — full drug profile →
- Erector spinae plane block — full drug profile →
- a rhomboid intercostal nerve block
- Bupivacaine (BUPIVACAINE) — full drug profile →
Conditions studied
- Analgesia — all drugs for Analgesia →
Sponsor
Zagazig University
Who can join
Adults 18 to 65, female only, with Analgesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Bilateral reduction mammoplasty is one of the most commonly performed breast surgery. The Postoperative pain following it should be minimized. Opioid administration for acute pain after reduction mammoplasty surgery has many side effects. Regional block techniques such as paravertebral block and thoracic epidural anesthesia have possible complications and technical difficulties. The new alternative regional techniques such as erector spinae plane block and rhomboid intercostal plane block are clinical trials for providing a safe, easy, and painless anesthetic procedure with adequate postoperative analgesia for a large section of patients undergoing thoracic surgeries.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Rhomboid intercostal block versus erector spinae plane block for perioperative analgesia in patients undergoing reduction mammoplasty: a prospective randomized study.
Abd Ellatif SE, Wahdan RA, Wahdan RA, Ibrahim ES, et al · · 2026 · PMID 41652322 · DOI 10.1186/s12871-025-03567-0
Verify or expand the search:
- PubMed search for NCT06225895
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Zagazig University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06225895 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zagazig University
- Last refreshed: 17 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06225895.
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