NCT06223828 (CR-AZI Kids) is a Phase 2, PHASE3 clinical trial of Azithromycin in Pediatric Asthma, sponsored by Johns Hopkins All Children's Hospital.

Who is sponsoring NCT06223828?

NCT06223828 is sponsored by Johns Hopkins All Children's Hospital.

What drugs are being tested in NCT06223828?

Interventions in NCT06223828: Azithromycin.

What condition does NCT06223828 study?

NCT06223828 studies Pediatric Asthma, Critical Illness.

Is NCT06223828 still recruiting?

NCT06223828 is currently recruiting now. Last updated 17 December 2025.

Last reviewed 2025-12-17 · How we verify

NCT06223828: CR-AZI Kids

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Azithromycin for Critical Asthma - Pediatrics

Recruiting now Phase 2, PHASE3 Last updated 17 December 2025

What this trial tests

Phase 2, PHASE3 trial testing Azithromycin in Pediatric Asthma in 100 participants. Currently enrolling.

Timeline

2 April 2024

Primary endpoint
31 July 2026

31 December 2026

Quick facts

Lead sponsor	Johns Hopkins All Children's Hospital
Phase	Phase 2, PHASE3
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	2 April 2024
Primary completion	31 July 2026
Estimated completion	31 December 2026
Sites	1 location across United States

Drugs / interventions tested

Azithromycin (azithromycin) — full drug profile →

Conditions studied

Pediatric Asthma — all drugs for Pediatric Asthma →
Critical Illness — all drugs for Critical Illness →

Sponsor

Johns Hopkins All Children's Hospital

Who can join

Adults 3 to 17, any sex, with Pediatric Asthma or Critical Illness. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The CR-AZI Study will assess the immunomodulatory effects of Azithromycin for pediatric Critical Asthma.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Azithromycin

Trials testing the same drug.

NCT07306234 — Doxycycline vs. Macrolide for MRMP (DOMINO) · Phase 4 · not yet recruiting
NCT06461429 — PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] · NA · not yet recruiting
NCT07164131 — Azithromycin Versus Doxycycline in Hospitalized Adult Patients With Community Acquired Pneumonia Treated With Beta-lacta · Phase 4 · recruiting
NCT07052942 — Individualizing Treatment for Asthma in Primary Care (Full Study) · Phase 4 · recruiting
NCT07213765 — Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease · Phase 4 · recruiting

Other recruiting trials for Pediatric Asthma

Currently open trials in the same condition.

NCT07381790 — Modern Technologies in Lower Respiratory Tract Infections in Children · recruiting
NCT06903897 — Social Needs Screening and Chronic Diseases Study (WE CARE) · NA · recruiting
NCT07500532 — Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma · NA · recruiting
NCT05999032 — The Puerto Rico Asthma Integrated Response Program ("PR-AIR") · NA · recruiting
NCT05945355 — Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA) · NA · recruiting

Other Johns Hopkins All Children's Hospital trials

Trials by the same sponsor.

NCT06628778 — Collaborative Risk-stratified Investigation in Teen Inpatients With Critical Illness: Anticoagulation With LMWH in Kids · Phase 3 · not yet recruiting
NCT07455396 — Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Ped · Phase 2 · not yet recruiting
NCT06346782 — Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer · NA · recruiting
NCT05470517 — Antibiotic Instillation in Appendicitis · Phase 2 · completed
NCT05379439 — Family Connections · NA · withdrawn

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06223828 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins All Children's Hospital
Last refreshed: 17 December 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06223828.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing