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NCT06194773
The Effect of Totalfil and Neosealer Sealers on the Post-endodontic Pain
NA trial testing Totalfil in Irreversible Pulpitis in 39 participants. Completed in 6 January 2025.
6 December 2024
Quick facts
| Lead sponsor | Gulf Medical University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 39 |
| Start date | 26 June 2023 |
| Primary completion | 6 December 2024 |
| Estimated completion | 6 January 2025 |
| Sites | 1 location across United Arab Emirates |
Drugs / interventions tested
- Totalfil
- NeoSealer
- AH-Plus sealer
Conditions studied
- Irreversible Pulpitis — all drugs for Irreversible Pulpitis →
Sponsor
Gulf Medical University
Who can join
Adults 18 to 70, any sex, with Irreversible Pulpitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to evaluate the effect of Totalfil and Neosealer sealers on post-endodontic pain compared to AH plus sealer in mandibular molars with symptomatic irreversible pulpitis. The main question: do Totalfil and Neosealer sealers affect postoperative pain intensity after root canal treatment in mandibular molars with symptomatic irreversible pulpitis? Participants will undergo root canal treatment using totalfil, Neosealer, or AH-Plus sealer. Researchers will compare Totalfil, Neosealer, and AH-Plus to assess the intensity of post-endodontic pain.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06194773
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Irreversible Pulpitis
Currently open trials in the same condition.
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Other Gulf Medical University trials
Trials by the same sponsor.
- NCT07468747 — Influence of Implant Insertion Depth on Peri-implant Bone Changes Around Short Implants · NA · not yet recruiting
- NCT07468760 — Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration · NA · not yet recruiting
- NCT07468773 — Effect of Individually Trained Oral Prophylaxis (iTOP) on Gingival Health in Orthodontic Patients · NA · not yet recruiting
- NCT07196826 — Effect of Passive Versus Active Aquatic Therapy Compared With Conventional Physiotherapy for Chronic Low Back Pain · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06194773 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gulf Medical University
- Last refreshed: 18 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06194773.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing