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NCT07163975
Complete Pulpotomy and Root Canal Treatment Patients With Irreversible Pulpitis With Type 2 Diabetes Mellitus
NA trial testing complete pulpotomy in Type 2 Diabetes Mellitus (T2DM) in 106 participants. Currently enrolling.
1 May 2026
Quick facts
| Lead sponsor | Postgraduate Institute of Dental Sciences Rohtak |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 106 |
| Start date | 1 May 2025 |
| Primary completion | 1 May 2026 |
| Estimated completion | 1 May 2027 |
| Sites | 1 location across India |
Drugs / interventions tested
- complete pulpotomy
- Root canal treatment
Conditions studied
- Type 2 Diabetes Mellitus (T2DM) — all drugs for Type 2 Diabetes Mellitus (T2DM) →
- Irreversible Pulpitis — all drugs for Irreversible Pulpitis →
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Who can join
Adults 18 to 70, any sex, with Type 2 Diabetes Mellitus (T2DM) or Irreversible Pulpitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
there is limited endodontic research on the effects of DM on pulp tissues. Diabetic human and animal histological research have demonstrated decreased wound repair, chronic pulp inflammation and reduced dentin bridge formation. To date, no human clinical trial has examined the impact of diabetes mellitus on teeth with irreversible pulpitis. Due to the paucity of data in the literature, there is a clinical dilemma whether to recommend root canal therapy or vital pulp therapy in diabetic patients with irreversible pulpitis. To the best of our knowledge, no prospective study has evaluated the outcome of complete pulpotomy versus root canal treatment in T2DM patients with irreversible pulpitis. The aim of this study is to compare and evaluate the success rates of pulpotomy and root canal treatment in type 2 diabetes mellitus patients in mature permanent teeth presenting with clinical symptoms of irreversible pulpitis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07163975
- Europe PMC full search
- ASCO Meeting Library
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- bioRxiv preprints
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Other Postgraduate Institute of Dental Sciences Rohtak trials
Trials by the same sponsor.
- NCT07412067 — Healing of Apicomarginal Defects Using Autograft or Allograft With Collagen Membrane · NA · not yet recruiting
- NCT07381595 — Role of Subgingival Instrumentation in Oral Lichen Planus · NA · not yet recruiting
- NCT07300124 — Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis · NA · not yet recruiting
- NCT07506135 — Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars. · NA · completed
- NCT07179835 — To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07163975 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Postgraduate Institute of Dental Sciences Rohtak
- Last refreshed: 9 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07163975.
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