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NCT06191874
Evaluation of Advanced Imaging and Visualization for Clinical Deep Brain Stimulation
trial testing Standard-of-care (SOC) surgery plan in Deep Brain Stimulation in 20 participants. Completed in 29 May 2025.
29 May 2025
Quick facts
| Lead sponsor | Duke University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 1 March 2024 |
| Primary completion | 29 May 2025 |
| Estimated completion | 29 May 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Standard-of-care (SOC) surgery plan
- HoloDBS hypothetical surgery plan
Conditions studied
- Deep Brain Stimulation — all drugs for Deep Brain Stimulation →
Sponsor
Duke University
Who can join
18 and older, any sex, with Deep Brain Stimulation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this project is to evaluate next generation visualization tools and surgical targeting models for clinical deep brain stimulation (DBS). This study will evaluate the performance of HoloDBS software in comparison to the current standard (SOC) clinical planning tools to prepare for DBS surgery. The investigators hypothesize that HoloDBS will provide more detailed and anatomically useful information to the neurosurgeon and neurologist than the current clinical standard. The study team reviews electronic medical records (EMR) from patients who are undergoing DBS surgery. There are no study visits involved in this study as only data from standard clinical care will be used. All study activities are executed by the study team and there are no interventions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06191874
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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- NCT07176494 — Revision of Deep Brain Stimulator in Patients With Parkinson's Disease · NA · recruiting
- NCT06960096 — Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study · recruiting
Other Duke University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06191874 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Duke University
- Last refreshed: 24 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06191874.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing