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NCT06147388: RECER

Regression of Cervical Precancerous Lesions and Associated Risk Factors

Recruiting now Last updated 25 February 2026
What this trial tests

trial testing Colposcopy in Cervix Uteri SIL in 300 participants. Currently enrolling.

Timeline
1 September 2022
Primary endpoint
1 July 2026
1 July 2027

Quick facts

Lead sponsorGeneral University Hospital, Prague
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment300
Start date1 September 2022
Primary completion1 July 2026
Estimated completion1 July 2027
Sites1 location across Czechia

Drugs / interventions tested

Conditions studied

Sponsor

General University Hospital, Prague

Who can join

Adults 18 to 40, female only, with Cervix Uteri SIL or HPV. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and identify predictive parameters associated with regression. Based on this analysis, a model will be proposed to predict the likelihood of lesion regression.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Regression of high-grade squamous intraepithelial cervical lesions and associated risk factors (RECER).
    Dostalek L, Brynda D, Marek R, Hederlingova J, et al · · 2025 · PMID 40215795 · DOI 10.1016/j.ijgc.2025.101768

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Other trials of Colposcopy

Trials testing the same drug.

Other General University Hospital, Prague trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06147388.

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