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NCT06147089: GRIP
Shift Work Intervention Strategies for Night Shift Workers
NA trial testing Sleep Intervention in Shift-Work Related Sleep Disturbance in 57 participants. Completed in 11 February 2025.
11 February 2025
Quick facts
| Lead sponsor | Erasmus Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 57 |
| Start date | 9 February 2023 |
| Primary completion | 11 February 2025 |
| Estimated completion | 11 February 2025 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Sleep Intervention
- Nutritional intervention
Conditions studied
- Shift-Work Related Sleep Disturbance — all drugs for Shift-Work Related Sleep Disturbance →
Sponsor
Erasmus Medical Center
Who can join
Adults 18 to 60, any sex, with Shift-Work Related Sleep Disturbance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this intervention study is to test behavioral interventions in night shift workers. The main question it aims to answer is: • Can personalized sleep or nutrition intervention strategies help against the negative health effects of night shift work? Participants will be followed before and after the intervention. Participants will wear smart devices, do a alertness/performance test and complete questionnaires. Blood samples will be collected. Researchers will compare the intervention groups to the control group (which receives no intervention) to see if the sleep and nutrition interventions affected the health of night shift workers.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Personalized sleep and nutritional strategies to combat adverse effects of night shift work: a controlled intervention protocol.
van der Rhee M, Oosterman JE, Wopereis S, van der Horst GTJ, et al · · 2024 · cited 2× · PMID 39300419 · DOI 10.1186/s12889-024-20022-w -
"Feeding the Rhythm"-Effects of Food and Nutrients on Daily Cortisol Secretion: From Molecular Mechanisms to Clinical Impact.
Paragliola RM, Marchetti M, Montagna C, Corsello SM, et al · · 2025 · cited 1× · PMID 41303713 · DOI 10.3390/ijms262211230
Verify or expand the search:
- PubMed search for NCT06147089
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06147089 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erasmus Medical Center
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06147089.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing