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NCT06147089: GRIP

Shift Work Intervention Strategies for Night Shift Workers

Completed NA Last updated 8 September 2025
What this trial tests

NA trial testing Sleep Intervention in Shift-Work Related Sleep Disturbance in 57 participants. Completed in 11 February 2025.

Timeline
9 February 2023
Primary endpoint
11 February 2025
11 February 2025

Quick facts

Lead sponsorErasmus Medical Center
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposeprevention
Enrollment57
Start date9 February 2023
Primary completion11 February 2025
Estimated completion11 February 2025
Sites1 location across Netherlands

Drugs / interventions tested

Conditions studied

Sponsor

Erasmus Medical Center

Who can join

Adults 18 to 60, any sex, with Shift-Work Related Sleep Disturbance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this intervention study is to test behavioral interventions in night shift workers. The main question it aims to answer is: • Can personalized sleep or nutrition intervention strategies help against the negative health effects of night shift work? Participants will be followed before and after the intervention. Participants will wear smart devices, do a alertness/performance test and complete questionnaires. Blood samples will be collected. Researchers will compare the intervention groups to the control group (which receives no intervention) to see if the sleep and nutrition interventions affected the health of night shift workers.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Personalized sleep and nutritional strategies to combat adverse effects of night shift work: a controlled intervention protocol.
    van der Rhee M, Oosterman JE, Wopereis S, van der Horst GTJ, et al · · 2024 · cited 2× · PMID 39300419 · DOI 10.1186/s12889-024-20022-w
  2. "Feeding the Rhythm"-Effects of Food and Nutrients on Daily Cortisol Secretion: From Molecular Mechanisms to Clinical Impact.
    Paragliola RM, Marchetti M, Montagna C, Corsello SM, et al · · 2025 · cited 1× · PMID 41303713 · DOI 10.3390/ijms262211230

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Other trials of Sleep Intervention

Trials testing the same drug.

Other Erasmus Medical Center trials

Trials by the same sponsor.

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Data sources for this page

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