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NCT06144736

PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND

Recruiting now Phase 2 Last updated 15 September 2025
What this trial tests

Phase 2 trial testing Robot-assisted retroperitoneal lymph node dissection in Seminoma in 60 participants. Currently enrolling.

Timeline
28 August 2023
Primary endpoint
31 August 2026
31 August 2029

Quick facts

Lead sponsorHeinrich-Heine University, Duesseldorf
PhasePhase 2
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment60
Start date28 August 2023
Primary completion31 August 2026
Estimated completion31 August 2029
Sites1 location across Germany

Drugs / interventions tested

Conditions studied

Sponsor

Heinrich-Heine University, Duesseldorf

Who can join

Adults 18 to 99, male only, with Seminoma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

PRIMETEST II is an interventional study involving low-volume metastatic seminoma. It explores a novel approach using robot-assisted primary retroperitoneal lymph node dissection, aiming to reduce long-term side effects and improve quality of life. By identifying factors predicting cancer recurrence, the study hopes to tailor treatments for better outcomes. The approach could potentially spare patients from chemotherapy induced long-term side effects while maintaining excellent survival rates, presenting a promising shift in testicular cancer care for this specific patient group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Matched-pair analysis of peri-operative and oncological outcomes of robot-assisted vs open retroperitoneal lymph node dissection.
    Pongratanakul P, Vermeulen-Spohn M, Wöltjen C, Thy S, et al · · 2025 · cited 5× · PMID 40260829 · DOI 10.1111/bju.16747

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Other recruiting trials for Seminoma

Currently open trials in the same condition.

Other Heinrich-Heine University, Duesseldorf trials

Trials by the same sponsor.

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Data sources for this page

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