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NCT06144736
PRIMETEST II - Clinical Stage II A/B Seminoma Treated With RA-RPLND
Phase 2 trial testing Robot-assisted retroperitoneal lymph node dissection in Seminoma in 60 participants. Currently enrolling.
31 August 2026
Quick facts
| Lead sponsor | Heinrich-Heine University, Duesseldorf |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 28 August 2023 |
| Primary completion | 31 August 2026 |
| Estimated completion | 31 August 2029 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Robot-assisted retroperitoneal lymph node dissection
- Adjuvant therapy with one cycle of cisplatin, etoposide and bleomycin — full drug profile →
Conditions studied
- Seminoma — all drugs for Seminoma →
Sponsor
Heinrich-Heine University, Duesseldorf
Who can join
Adults 18 to 99, male only, with Seminoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
PRIMETEST II is an interventional study involving low-volume metastatic seminoma. It explores a novel approach using robot-assisted primary retroperitoneal lymph node dissection, aiming to reduce long-term side effects and improve quality of life. By identifying factors predicting cancer recurrence, the study hopes to tailor treatments for better outcomes. The approach could potentially spare patients from chemotherapy induced long-term side effects while maintaining excellent survival rates, presenting a promising shift in testicular cancer care for this specific patient group.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Matched-pair analysis of peri-operative and oncological outcomes of robot-assisted vs open retroperitoneal lymph node dissection.
Pongratanakul P, Vermeulen-Spohn M, Wöltjen C, Thy S, et al · · 2025 · cited 5× · PMID 40260829 · DOI 10.1111/bju.16747
Verify or expand the search:
- PubMed search for NCT06144736
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Seminoma
Currently open trials in the same condition.
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- NCT05529251 — De-escalation Study for Stage IIa/IIb < 3 cm Seminoma · Phase 2 · recruiting
- NCT05142982 — Radiotherapy vs Observation for Post Chemotherapy Residual Mass in Advanced Seminoma · NA · recruiting
Other Heinrich-Heine University, Duesseldorf trials
Trials by the same sponsor.
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- NCT07455097 — COMBINED PSMA-PET/CT AND MRI STAGING IN INTERMEDIATE AND HIGH-RISK PATIENTS PROSTATA-CANCER (COMBINE-P) · active not recruiting
- NCT07254663 — GEL & MEDication Dysphagia · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06144736 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Heinrich-Heine University, Duesseldorf
- Last refreshed: 15 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06144736.
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