NCT06313944 (GE-R-A-TPS) is a clinical trial of Registry in Alzheimer Disease, sponsored by Heinrich-Heine University, Duesseldorf.

Who is sponsoring NCT06313944?

NCT06313944 is sponsored by Heinrich-Heine University, Duesseldorf.

What drugs are being tested in NCT06313944?

Interventions in NCT06313944: Registry.

What condition does NCT06313944 study?

NCT06313944 studies Alzheimer Disease.

Is NCT06313944 still recruiting?

NCT06313944 is currently recruiting now. Last updated 26 November 2025.

Last reviewed 2025-11-26 · How we verify

NCT06313944: GE-R-A-TPS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

German Registry of Alzheimer's Disease Treated With Transcranial Pulse Stimulation

Recruiting now Last updated 26 November 2025

What this trial tests

trial testing Registry in Alzheimer Disease in 100 participants. Currently enrolling.

Timeline

6 August 2025

Primary endpoint
1 October 2026

1 October 2026

Quick facts

Lead sponsor	Heinrich-Heine University, Duesseldorf
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	100
Start date	6 August 2025
Primary completion	1 October 2026
Estimated completion	1 October 2026
Sites	4 locations across Germany

Drugs / interventions tested

Registry — full drug profile →

Conditions studied

Alzheimer Disease — all drugs for Alzheimer Disease →

Sponsor

Heinrich-Heine University, Duesseldorf

Who can join

Adults 18 to 85, any sex, with Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will primarily investigate the safety and secondarily the effect and applicability of Transcranial Pulse Wave Stimulation (TPS) for the treatment of Alzheimer's disease in the context of a PMCF study (Post-Market Clinical Follow-up). The multicenter, prospective data collection should help to optimize the stimulation protocol, as well as to record frequent to occasional adverse effects of the product and cognitive, affective and subjective scores.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Current state of clinical ultrasound neuromodulation.
Matt E, Radjenovic S, Mitterwallner M, Beisteiner R. · · 2024 · cited 27× · PMID 38962179 · DOI 10.3389/fnins.2024.1420255
Neuromodulatory Effects of Transcranial Pulse Stimulation (TPS) in Neurological and Psychiatric Disorders-A Systematic Review and Meta-Analysis.
Polte S, Klingmann L, Seßmann A, Schwichtenberg S, et al · · 2025 · cited 1× · PMID 41295447 · DOI 10.3390/neurolint17110188

Verify or expand the search:

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Currently open trials in the same condition.

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NCT06930560 — HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms · NA · recruiting

Other Heinrich-Heine University, Duesseldorf trials

Trials by the same sponsor.

NCT04993508 — Randomized Prospective Multi Center Cohort Study for Primary Diagnosis of Clinically Significant Prostate Cancer With Co · NA · not yet recruiting
NCT07385482 — Chronic and Acute Cardiovascular Diseases in Elderly Intensive Care Patients · not yet recruiting
NCT07455097 — COMBINED PSMA-PET/CT AND MRI STAGING IN INTERMEDIATE AND HIGH-RISK PATIENTS PROSTATA-CANCER (COMBINE-P) · active not recruiting
NCT07254663 — GEL & MEDication Dysphagia · recruiting
NCT07372820 — METABolic Deterioration in HTX Determines Outcomes · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06313944 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Heinrich-Heine University, Duesseldorf
Last refreshed: 26 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06313944.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing