NCT06125626 is a Phase 2 clinical trial of Probiotical in Diarrhea, sponsored by University of Palermo.

Who is sponsoring NCT06125626?

NCT06125626 is sponsored by University of Palermo.

What drugs are being tested in NCT06125626?

Interventions in NCT06125626: Probiotical, Placebo.

Is NCT06125626 still recruiting?

NCT06125626 is currently completed. Last updated 13 November 2023.

Last reviewed 2023-11-13 · How we verify

NCT06125626

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prevention of Traveler's Diarrhea

Completed Phase 2 Last updated 13 November 2023

What this trial tests

Phase 2 trial testing Probiotical in Diarrhea in 3 participants. Completed in 10 October 2023.

Timeline

10 July 2023

Primary endpoint
7 October 2023

10 October 2023

Quick facts

Lead sponsor	University of Palermo
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	prevention
Enrollment	3
Start date	10 July 2023
Primary completion	7 October 2023
Estimated completion	10 October 2023
Sites	1 location across Italy

Drugs / interventions tested

Probiotical
Placebo

Conditions studied

Diarrhea — all drugs for Diarrhea →

Sponsor

University of Palermo

Who can join

Eligibility, male only, with Diarrhea. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The prevention of traveller's diarrhea makes use of the selection of foods and drinks, the purification of water, the use of pharmacological substances such as bismuth salicylate and rifaximin (which can only be taken for short periods). The very attractive prospect of preventing travellers' diarrhea without systemic antibiotics has fueled interest in probiotics for this purpose. However, not all probiotics are identical, and the results of studies conducted with a particular agent cannot be generalized to indicate that any probiotic agent would be successful in the same clinical situation. Probiotics such as Lactobacillus GG have been shown to reduce the incidence of diarrhea in travelers in randomized controlled trials. In contrast, another Lactobacillus preparation, non-viable Lactobacillus acidophilus, showed no benefit over placebo in a randomized, double-blind, controlled trial of 174 travelers. The reasons for this are unclear, but could be related to the fact that the bacteria were not viable or a peculiarity of the strain selected for testing.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Diarrhea

Currently open trials in the same condition.

NCT07285785 — Rifaximin 200 mg Plus Oral Rehydration vs Oral Rehydration Alone in Children With Acute Diarrhea · Phase 4 · recruiting
NCT07385196 — Defining Ileorectal Syndrome: a Prospective Observational Study · recruiting
NCT07205926 — First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Yo · Phase 1 · recruiting
NCT07484412 — Efficacy and Safety of Encapsulated Bifidobacterium Longum BBH016 in Subjects With Lower Gastrointestinal Symptoms · NA · active not recruiting
NCT06801067 — A Study of SER-155 to Treat Diarrhea in People on Immunotherapy · Phase 1 · recruiting

Other University of Palermo trials

Trials by the same sponsor.

NCT03017716 — Inflammatory Back Pain and Gluten Free Diet · NA · not yet recruiting
NCT07364149 — Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metaboli · NA · recruiting
NCT06206616 — Liver Steatosis in Pediatric CD Patients · not yet recruiting
NCT07433543 — Foam Rolling, Blood Pressure and Range of Motion · NA · completed
NCT07213011 — Effects of Static Stretching and Self-myofascial Release on Local and Remote Range of Motion · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06125626 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Palermo
Last refreshed: 13 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06125626.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing