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NCT07433543
Foam Rolling, Blood Pressure and Range of Motion
NA trial testing Cervical foam rolling in Healthy Participants in 24 participants. Completed in 31 July 2025.
30 July 2025
Quick facts
| Lead sponsor | University of Palermo |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 24 |
| Start date | 26 May 2025 |
| Primary completion | 30 July 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Cervical foam rolling
Conditions studied
- Healthy Participants — all drugs for Healthy Participants →
- Healthy Young Adults — all drugs for Healthy Young Adults →
Sponsor
University of Palermo
Who can join
18 and older, any sex, with Healthy Participants or Healthy Young Adults. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Foam rolling (FR) is a technique involving the application of external pressure to muscles and connective tissues using different devices (e.g. foam rollers, massage rollers, balls, etc.) , with the aim of reducing muscle tension, soreness, and stiffness, and improving circulation, and flexibility. Emerging evidence suggests that FR may also enhance tissue perfusion and blood flow and could induce a relaxation response, potentially modulating autonomic balance toward increased parasympathetic activity. The cervical region is of particular interest due to the presence of clinically relevant vascular structures, such as the carotid arteries, whose mechanical stimulation may elicit cardiovascular responses. Accordingly, the present study was designed to investigate the acute effects of cervical foam rolling on blood pressure, while simultaneously examining tissue hardness and heart rate variability as potential underlying mediators, and to explore a possible dose-response relationship between foam rolling volume and blood pressure through an inter-set analysis. Additionally, the acute effects of cervical foam rolling on local range of movement were also investigated.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07433543
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07433543 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Palermo
- Last refreshed: 25 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07433543.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing