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NCT06110611
Monolithic Zirconia With CAD/CAM Titanium Abutments: A 5-year Prospective Case Series Study
trial testing Astra Tech Osseospeed EV® dental implant in Edentulous Alveolar Ridge in 50 participants. Enrolling by invitation.
1 June 2025
Quick facts
| Lead sponsor | University Medical Center Groningen |
|---|---|
| Status | ENROLLING BY INVITATION |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 October 2024 |
| Primary completion | 1 June 2025 |
| Estimated completion | 1 June 2026 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Astra Tech Osseospeed EV® dental implant
Conditions studied
- Edentulous Alveolar Ridge — all drugs for Edentulous Alveolar Ridge →
Sponsor
University Medical Center Groningen
Who can join
18 and older, any sex, with Edentulous Alveolar Ridge. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
* Background There is a growing interest in restoring function in the posterior maxilla and mandible with dental implants. Next to this, these implants must be restored with crowns which are subject to minimal complications. Companies have introduced the option of screw-retaining and zirconia as crown material. The combination of posterior implants and screw-retained zirconia crowns are widely used, but prospective research on clinical performance and patient centered outcomes are scarce. Even more, 5-years data are lacking. * Main research question To evaluate the clinical performance of Astra Tech Implants EV and Atlantis CustomBase Abutments with full-contour zirconia Atlantis Crowns in the posterior maxilla and mandible. The primary objective of the study is marginal bone level changes by radiological assessments at 5-years follow-up. Secondary objectives are implant and restoration survival, condition of peri- implant mucosa and patients' satisfaction. * Design (including population, confounders/outcomes) The study design is an observational study of a group of patients which were treated 5 years ago with a dental implant and a screw-retained implant-supported zirconia restoration because of a missing tooth in the posterior region. Outcomes: primary outcome is the change in marginal peri-implant bone level 5 years after placing the definitive restoration. Secondary outcome measures will be implant and restoration survival, peri-implant mucosa health and patients' satisfaction using a questionnaire.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06110611
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Other University Medical Center Groningen trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06110611 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Medical Center Groningen
- Last refreshed: 30 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06110611.
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