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NCT06103474: CRANE
Clinical Reporting to Alleviate the Nocebo Effect
NA trial testing Lumbar Magnetic Resonance Imaging (MRI) in Nocebo Effect in 18 participants. Completed in 11 November 2025.
11 November 2025
Quick facts
| Lead sponsor | University of Alabama at Birmingham |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 18 |
| Start date | 14 January 2024 |
| Primary completion | 11 November 2025 |
| Estimated completion | 11 November 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Lumbar Magnetic Resonance Imaging (MRI)
Conditions studied
- Nocebo Effect — all drugs for Nocebo Effect →
Sponsor
University of Alabama at Birmingham
Who can join
18 and older, any sex, with Nocebo Effect. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Terminology in radiology reports may cause patients harm by anchoring to or justifying a particular diagnosis. This phenomenon is known as the nocebo effect. MRI may cause patients to pursue more invasive procedures with little added benefit. This study aims to reproduce a study to determine the impact of clinical reporting on patient care and outcomes for those suffering from lower back pain.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06103474
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Alabama at Birmingham trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06103474 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alabama at Birmingham
- Last refreshed: 23 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06103474.
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