Last reviewed · How we verify
NCT06103422
Change in Taste Sensation After Orthognathic Surgery
NA trial testing Whole mouth taste tests in Orthognathic Surgery in 35 participants. Completed in 25 November 2021.
22 January 2021
Quick facts
| Lead sponsor | Yağmur Malkoc |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 35 |
| Start date | 17 July 2020 |
| Primary completion | 22 January 2021 |
| Estimated completion | 25 November 2021 |
| Sites | 2 locations across Turkey (Türkiye) |
Drugs / interventions tested
- Whole mouth taste tests
- Localized taste tests
Conditions studied
- Orthognathic Surgery — all drugs for Orthognathic Surgery →
- Altered Taste — all drugs for Altered Taste →
Sponsor
Yağmur Malkoc
Who can join
Adults 17 to 42, any sex, with Orthognathic Surgery or Altered Taste. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Orthognathic surgery refers to jaw operations that can be performed on the upper jaws (Le Fort I osteotomy) and lower jaws (Sagittal Split Ramus osteotomy). In orthognathic surgery practice, taste perception could be affected by potential damage to peripheral nerves that conduct chemosensory information regarding gustation from the palate and tongue. This study aimed to evaluate the changes in the sense of taste after Le Fort I osteotomy, Sagittal Split Ramus osteotomy, and bimaxillary surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Change in taste sensation after orthognathic surgery.
Malkoc Y, Gulsever S, Uckan S. · · 2024 · PMID 38558265 · DOI 10.1007/s00784-024-05626-1
Verify or expand the search:
- PubMed search for NCT06103422
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT05708521 — Personalization of Opioid Prescription Following Orthognathic Surgery · Phase 4 · active not recruiting
Other Yağmur Malkoc trials
Trials by the same sponsor.
- NCT06768281 — Effect of Lidocaine and Ozone in Injection for Myofascial Pain · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06103422 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yağmur Malkoc
- Last refreshed: 26 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06103422.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing