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NCT06079606
The Effects of Antibiotic Exposure in Early Infancy on Vaccine Responses
trial testing Antibiotic treatment in Immune Responses in 200 participants. Participants enrolled and being followed up; not accepting new ones.
28 February 2025
Quick facts
| Lead sponsor | Landspitali University Hospital |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 10 September 2022 |
| Primary completion | 28 February 2025 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across Iceland |
Drugs / interventions tested
- Antibiotic treatment — full drug profile →
Conditions studied
- Immune Responses — all drugs for Immune Responses →
- Antibiotic Treatment — all drugs for Antibiotic Treatment →
Sponsor
Landspitali University Hospital
Who can join
Under 6 Weeks, any sex, with Immune Responses or Antibiotic Treatment. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This prospective cohort study will include 200 term children born in Landspitali University Hospital in Iceland. The cohort will be divided into four groups according to antibiotic exposure of which one is the control group. Children's immune responses to live oral rotavirus vaccine as well as conventional vaccinations given at three, five and 12 months old will be determined by measuring salivary and serologic responses. Responses will be compared between the four groups. Stool samples will also be collected from participants and the composition of the microbiome compared between the four groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06079606
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other Landspitali University Hospital trials
Trials by the same sponsor.
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- NCT06915493 — Blood Glucose Levels in Children During Anesthesia · completed
- NCT06050408 — Assessment of LF-rTMS in Patients With Visual Neglect · NA · unknown
- NCT06929026 — Retinal Biomarkers in Parkinson´s Disease · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06079606 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Landspitali University Hospital
- Last refreshed: 18 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06079606.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing