Last reviewed · How we verify
NCT02916134: COMMA
Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis
NA trial testing Laparoscopic +/- Open Appendicectomy in Appendicitis in 186 participants. Completed in 8 December 2019.
8 December 2019
Quick facts
| Lead sponsor | Beaumont Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 186 |
| Start date | 12 September 2016 |
| Primary completion | 8 December 2019 |
| Estimated completion | 8 December 2019 |
| Sites | 1 location across Ireland |
Drugs / interventions tested
- Laparoscopic +/- Open Appendicectomy
- Antibiotic treatment — full drug profile →
Conditions studied
- Appendicitis — all drugs for Appendicitis →
Sponsor
Beaumont Hospital
Who can join
Adults 18 to 80, any sex, with Appendicitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to compare antibiotic treatment versus surgery for patients with uncomplicated appendicitis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Appendectomy versus antibiotic treatment for acute appendicitis.
Doleman B, Fonnes S, Lund JN, Boyd-Carson H, et al · · 2024 · cited 9× · PMID 38682788 · DOI 10.1002/14651858.cd015038.pub2
Verify or expand the search:
- PubMed search for NCT02916134
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Appendicitis
Currently open trials in the same condition.
- NCT07115303 — Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure · NA · recruiting
- NCT06395636 — Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients · NA · recruiting
- NCT07049965 — Comparative Study of Harmonic Scalpel vs. Suture Ligation for Appendix Base During Laparoscopic Appendectomy · NA · active not recruiting
- NCT07478029 — Clinical Study of PEG Bowel Preparation in Appendectomy Patients · recruiting
- NCT06177418 — Transumbilical Laparoscopic Appendectomy · NA · recruiting
Other Beaumont Hospital trials
Trials by the same sponsor.
- NCT07236359 — Evaluation of Well Being and Patient Reported Outcomes After Robotic Single-port Nipple Sparing Mastectomy and Implant R · NA · not yet recruiting
- NCT07230535 — Evaluation of Wellbeing and Patient Reported Outcomes After Open vs Robotic Mastectomy With DIEP Reconstruction · NA · recruiting
- NCT05384314 — A Retrospective Study to Evaluate the Predictability of Abnormal Arterial Blood Gas Measurements Through Novel Observati · unknown
- NCT03286855 — Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD) · NA · completed
- NCT04025242 — Objective Assessment of Adherence to Inhalers by COPD Patients · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02916134 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Beaumont Hospital
- Last refreshed: 13 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02916134.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing