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NCT06075797: PQ-ResPOND
The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial
NA trial testing PediQUEST ResPOND in Cerebral Palsy Infantile in 54 participants. Completed in 31 July 2025.
15 July 2025
Quick facts
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 54 |
| Start date | 8 May 2024 |
| Primary completion | 15 July 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 4 locations across United States, Australia |
Drugs / interventions tested
- PediQUEST ResPOND
Conditions studied
- Cerebral Palsy Infantile — all drugs for Cerebral Palsy Infantile →
- Disabilities Multiple — all drugs for Disabilities Multiple →
- Pain — all drugs for Pain →
Sponsor
Massachusetts General Hospital
Who can join
1 and older, any sex, with Cerebral Palsy Infantile or Disabilities Multiple. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this pilot randomized controlled trial is to test the feasibility of running a full scale randomized controlled trial that compares the effect of the PQ-ResPOND intervention versus usual care to improve recurrent pain in children, adolescents, and young adults with severe neurologic impairment. The main questions it aims to answer are: * Is the study feasible and acceptable for participants? * Does PQ-ResPOND have a potential to be effective? Participants will: * answer surveys (their parents will) telling us about the child's pain, symptoms, and use of complementary therapies, and about their own psychological distress and satisfaction with care. * a group will receive the PQ-ResPOND intervention which consists of: * activating parents and providers by using the PediQUEST system, a web platform that administers surveys and generates feedback reports alerting parents and providers about the child's experience, AND * responding to child pain or discomfort by incorporating the Response team (members of the hospital's palliative care team) into the child's care to privde a standardized approach to managing recurrent pain. Researchers will use a comparison (control) group consisting of participants who will answer surveys and receive usual care (no feedback reports or consult with palliative care in this group) to see if a randomized design is feasible.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06075797
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Cerebral Palsy Infantile
Currently open trials in the same condition.
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- NCT06947889 — Biofeedback Based System to Enhance Robotic Assisted Gait Training in Children With Cerebral Palsy · recruiting
Other Massachusetts General Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06075797 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
- Last refreshed: 21 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06075797.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing