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NCT06069791
Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1
Phase 1 trial testing Bupivacaine Injection in Post-Traumatic Headache in 12 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Yale University |
|---|---|
| Phase | Phase 1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | quadruple |
| Primary purpose | other |
| Enrollment | 12 |
| Start date | 26 January 2024 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Bupivacaine Injection — full drug profile →
Conditions studied
- Post-Traumatic Headache — all drugs for Post-Traumatic Headache →
Sponsor
Yale University
Who can join
18 and older, any sex, with Post-Traumatic Headache. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The acute and subacute sensations that occur on the scalp with injection of different concentrations of bupivacaine for grater occipital nerve blockade will be compared. Each Veteran participant will be randomized to receive three different concentrations, which will be injected one week apart each.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06069791
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Bupivacaine Injection
Trials testing the same drug.
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- NCT05980546 — Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty · Phase 4 · completed
- NCT05671172 — Effect of Adding Hyaluronidase to Bupivacaine in Transversus Abdominis Plane Block for Cesarean Section · NA · completed
Other recruiting trials for Post-Traumatic Headache
Currently open trials in the same condition.
- NCT05857761 — GAIN Symptoms: Post-traumatic Headache · NA · active not recruiting
- NCT06015451 — Exercise in Postconcussion Symptoms and Posttraumatic Headache · NA · recruiting
Other Yale University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06069791 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yale University
- Last refreshed: 29 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06069791.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing