Last reviewed · How we verify
NCT06066996
Evaluation of the Electronic Cigarette Withdrawal Syndrome
EARLY_PHASE1 trial testing Transdermal Nicotine Patch in E-cigarette Use in 150 participants. Currently enrolling.
30 June 2028
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 150 |
| Start date | 28 November 2023 |
| Primary completion | 30 June 2028 |
| Estimated completion | 30 June 2028 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Transdermal Nicotine Patch — full drug profile →
- Placebo Nicotine Patch
Conditions studied
- E-cigarette Use — all drugs for E-cigarette Use →
- Withdrawal — all drugs for Withdrawal →
Sponsor
Johns Hopkins University
Who can join
Adults 21 to 55, any sex, with E-cigarette Use or Withdrawal. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this project is to rigorously evaluate the nature of e-cigarette withdrawal in exclusive e-cigarette users during a monitored abstinence period and the role of nicotine in the expression of this withdrawal syndrome.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06066996
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transdermal Nicotine Patch
Trials testing the same drug.
- NCT06218823 — Tobacco Treatment Comparison for Cancer Care · Phase 4 · completed
- NCT05746273 — Depressed Mood Improvement Through Nicotine Dosing 3 · Phase 2 · recruiting
- NCT03072511 — Smoking Cessation Intervention · Phase 4 · terminated
Other recruiting trials for E-cigarette Use
Currently open trials in the same condition.
- NCT07161050 — Effects of a Low Nicotine Standard and Tobacco Prices on Illegal Cigarette Purchasing · NA · recruiting
- NCT07040566 — A Trial of Varenicline for E-cigarette Cessation · Phase 2 · recruiting
- NCT06129123 — An Online Intervention to Reduce E-cigarette Use and Susceptibility to Smoking in Young Adults · NA · recruiting
- NCT05906082 — Vape-Free Text-Messaging: Pilot Study · NA · recruiting
Other Johns Hopkins University trials
Trials by the same sponsor.
- NCT06236542 — Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety · NA · not yet recruiting
- NCT07532252 — Daridorexant for Alcohol Use Disorder · Phase 2 · not yet recruiting
- NCT06687655 — Impact of Exogenous Ketones on Sleep Apnea · Phase 1, PHASE2 · not yet recruiting
- NCT07079111 — 3D Printed Occlusal Splints for Intraoperative Use · NA · not yet recruiting
- NCT02998502 — The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06066996 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 14 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06066996.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing