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NCT06054997
Anaesthesiologic Considerations for Intraoperative ECMO Anticoagulation During Lung Transplantation
trial in Lung Transplantation in 141 participants. Completed in 1 August 2023.
31 December 2022
Quick facts
| Lead sponsor | University Hospital, Motol |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 141 |
| Start date | 1 January 2020 |
| Primary completion | 31 December 2022 |
| Estimated completion | 1 August 2023 |
| Sites | 1 location across Czechia |
Conditions studied
- Lung Transplantation — all drugs for Lung Transplantation →
Sponsor
University Hospital, Motol
Who can join
Eligibility, any sex, with Lung Transplantation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Extracorporeal membrane oxygenation (ECMO) is a frequently used extracorporeal support measure during the intraoperative period in lung transplantation. A certain amount of anticoagulation, mainly unfractionated heparin (UFH), is used as part of ECMO support. One of the most common perioperative complications during lung transplantation is bleeding. An inadequately high dose of UFH can increase the risk of bleeding. In this study, the investigators hypothesised that a lower dose of UFH would decrease the risk of nonsurgical bleeding complications during lung transplantation and would not pose an increased risk of thrombotic complications for patients or ECMO circuits.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Anaesthesiologic Considerations for Intraoperative ECMO Anticoagulation During Lung Transplantation: A Single-Centre, Retrospective, Observational Study.
Vajter J, Holubova G, Novysedlak R, Svorcova M, et al · · 2024 · cited 7× · PMID 38585623 · DOI 10.3389/ti.2024.12752
Verify or expand the search:
- PubMed search for NCT06054997
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lung Transplantation
Currently open trials in the same condition.
- NCT07479511 — Adaptation of Lung Transplant Recipients at Extreme Altitude · active not recruiting
- NCT06853223 — This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction · Phase 2 · recruiting
- NCT06868823 — Prospective Observational Pilot Study of LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation · recruiting
- NCT07316829 — TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Re · active not recruiting
- NCT06327945 — Transplanting Lungs From Uncontrolled Donation After Circulatory Death · NA · recruiting
Other University Hospital, Motol trials
Trials by the same sponsor.
- NCT07149142 — Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes · NA · not yet recruiting
- NCT07482969 — Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids) · recruiting
- NCT06868823 — Prospective Observational Pilot Study of LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation · recruiting
- NCT06102421 — Evaluation of the Effectiveness of Extracorporeal Shockwave Therapy in Patients With Patellar Tendinopathy on Its Microm · completed
- NCT07103317 — Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06054997 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Motol
- Last refreshed: 3 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06054997.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing