Who is sponsoring NCT06048900?

NCT06048900 is sponsored by Dilek Cetinkaya.

What drugs are being tested in NCT06048900?

Interventions in NCT06048900: ultrasound guided optic nerve sheath diameter measurement.

What condition does NCT06048900 study?

NCT06048900 studies Intracranial Pressure Increase.

Is NCT06048900 still recruiting?

NCT06048900 is currently completed. Last updated 21 September 2023.

Last reviewed 2023-09-21 · How we verify

NCT06048900

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Effect of Trendelenburg Position Duration on Intracranial Pressure

Completed NA Last updated 21 September 2023

What this trial tests

NA trial testing ultrasound guided optic nerve sheath diameter measurement in Intracranial Pressure Increase in 25 participants. Completed in 15 October 2022.

Timeline

10 March 2021

Primary endpoint
15 September 2022

15 October 2022

Quick facts

Lead sponsor	Dilek Cetinkaya
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	screening
Enrollment	25
Start date	10 March 2021
Primary completion	15 September 2022
Estimated completion	15 October 2022
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

ultrasound guided optic nerve sheath diameter measurement

Conditions studied

Intracranial Pressure Increase — all drugs for Intracranial Pressure Increase →

Sponsor

Dilek Cetinkaya

Who can join

Adults 18 to 65, female only, with Intracranial Pressure Increase. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Lloyd Davies position is a position used in laparoscopic hysterectomies where the head is lowered 45 degrees and the legs are bent from the knee area.It is a version of the Trendelenburg position. Both this position and for laparoscopic surgery carbon dioxide (CO2) gas given into the abdomen, causes problems for the patient. Increased abdominal and thoracic pressure impairs venous return and increases intracranial pressure. Optic nerve sheath diameter can be measured by placing an ultrasound probe over the eye. It is possible to follow up the increase in intracranial pressure with this diameter measurement. In this study, it was planned to measure the optic nerve sheath diameter by ultrasound in patients who will undergo laparoscopic hysterectomy. It is aimed to observe the changes in the increase in intracranial pressure as the time lengthens with the measurements to be made at certain intervals during the operation. Secondary aim is to determine whether there is a cut-off value where the intracranial pressure starts to increase.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of the effect of trendelenburg position duration on intracranial pressure in laparoscopic hysterectomies using ultrasonographic optic nerve sheath diameter measurements.
Guloglu H, Cetinkaya D, Oge T, Bilir A. · · 2024 · cited 1× · PMID 39010013 · DOI 10.1186/s12871-024-02624-4

Verify or expand the search:

Other recruiting trials for Intracranial Pressure Increase

Currently open trials in the same condition.

NCT06855342 — Prospective Ocular Imaging for Intracranial Pressure Evaluation · recruiting
NCT06511804 — Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Pa · recruiting
NCT06464419 — Effect of Lithotomy Position on Optic Nerve Sheath Diameter · recruiting
NCT06288659 — aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial · NA · recruiting
NCT06403592 — The Effect of a Laryngeal Mask Airway on Optic Nerve Sheath Diameter · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06048900 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Dilek Cetinkaya
Last refreshed: 21 September 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06048900.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing