Last reviewed · How we verify
NCT06288659: ASTIM-MT
aSAH Treatment Based on Intraventricular ICP Monitoring: A Prospective, Multicenter, Randomized and Controlled Trial
NA trial testing Intraventricular intracranial pressure monitoring in Aneurysmal Subarachnoid Hemorrhage in 372 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | Huashan Hospital |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 372 |
| Start date | 20 May 2024 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 December 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Intraventricular intracranial pressure monitoring
Conditions studied
- Aneurysmal Subarachnoid Hemorrhage — all drugs for Aneurysmal Subarachnoid Hemorrhage →
- Intracranial Pressure Increase — all drugs for Intracranial Pressure Increase →
Sponsor
Huashan Hospital
Who can join
18 and older, any sex, with Aneurysmal Subarachnoid Hemorrhage or Intracranial Pressure Increase. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
ASTIM is a multicenter, prospective, randomised, blinded end-point assessed trial, to investigate the efficacy and safety of treatment based on intracranial pressure monitoring in improving the prognosis of patients with aneurysmal subarachnoid hemorrhage.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Beyond the bleed: complications after aneurysmal subarachnoid hemorrhage. Pathophysiology, clinical implications, and management strategies: a review.
Busl KM, Bogossian EG, Claassen J, Helbok R, et al · · 2025 · cited 4× · PMID 41029753 · DOI 10.1186/s13054-025-05640-z
Verify or expand the search:
- PubMed search for NCT06288659
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Aneurysmal Subarachnoid Hemorrhage
Currently open trials in the same condition.
- NCT06863480 — Tocilizumab-aazg for Hemorrhage: Reduction of Ischemic Vascular Events · Phase 1 · recruiting
- NCT06409364 — FLudrocortisone Administration in Aneurysmal Subarachnoid Haemorrhage · Phase 2 · recruiting
- NCT06494436 — Microvention AnEurysm & STroke Real-life Data cOllection · recruiting
- NCT06548477 — Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages · NA · recruiting
- NCT06284642 — Early Lumbar Drainage Combined With Intrathecal Urokinase Injection for Treatment of Severe Aneurysmal SAH (LD-ITUK) · Phase 4 · recruiting
Other Huashan Hospital trials
Trials by the same sponsor.
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- NCT07369830 — The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function · NA · recruiting
- NCT07185373 — Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL · Phase 2, PHASE3 · not yet recruiting
- NCT07075029 — RSV in Acute Respiratory Infection Surveillance Among Community-Dwelling Elderly Aged ≥50 Years in China · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06288659 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Huashan Hospital
- Last refreshed: 7 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06288659.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing