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NCT06030609: RINNOR
The Comparison Between Ringer Lactate Solution and Normal Saline With Dextrose Water in Post-Operative Period of Kidney Transplantation
Phase 3 trial testing Ringer's Lactate Crystalloid Solutions in Electrolyte Imbalance in 159 participants. Completed in 24 March 2026.
24 December 2025
Quick facts
| Lead sponsor | King Chulalongkorn Memorial Hospital |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 159 |
| Start date | 1 September 2024 |
| Primary completion | 24 December 2025 |
| Estimated completion | 24 March 2026 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Ringer's Lactate Crystalloid Solutions — full drug profile →
- Normal saline
Conditions studied
- Electrolyte Imbalance — all drugs for Electrolyte Imbalance →
- Kidney Transplant; Complications — all drugs for Kidney Transplant; Complications →
Sponsor
King Chulalongkorn Memorial Hospital
Who can join
18 and older, any sex, with Electrolyte Imbalance or Kidney Transplant; Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a randomized controlled pragmatic clinical trial. We aim to evaluate the effect of Ringer lactate solution (RLS) and normal saline solution (NSS) with dextrose water (D5W) on the electrolyte abnormality of kidney transplant recipients (KTR) during the first post-operative week. The problem with using NSS with or without D5W as a standard replacement fluid is the hyperchloremic metabolic acidosis which might compromise the kidney allograft function. A total 60 KTR will be enrolled and randomized to receive either RLS or NSS with D5W. The primary outcome is serum bicarbonate level at day 5 after transplantation. Secondary outcomes include the serum potassium, serum sodium, serum chloride, cytokine panel, and the incidence of delayed graft function.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06030609
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ringer's Lactate Crystalloid Solutions
Trials testing the same drug.
- NCT07239713 — Clinical Effects of Ringers Lactate Versus Sterofundin/ Plasmalyte Solution in Patients With Sepsis · NA · recruiting
- NCT06440772 — Portal Vein Pulsatility Index to Assess Fluid Intolerance · completed
Other King Chulalongkorn Memorial Hospital trials
Trials by the same sponsor.
- NCT07261228 — The Difference in Carbon Footprint Between Diagnostic Upper GI Endoscopy in Dyspeptic Patients Versus Therapeutic Upper · recruiting
- NCT07171853 — The Carbon Footprint Study of Colonoscopy · recruiting
- NCT06906835 — Comparing Reticulocyte Hemoglobin and Transferrin Saturation to Guide Iron Treatment in People on Dialysis · NA · recruiting
- NCT06288828 — The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients with Compensa · NA · active not recruiting
- NCT06326918 — Duodenal Microbiota in Functional Dyspepsia · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06030609 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by King Chulalongkorn Memorial Hospital
- Last refreshed: 17 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06030609.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing