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NCT06027918
The Effect of Altitude Difference on the Duration of Nerve Block; A Three-Center Study.
NA trial testing Infraclavicular brachial plexus block in Forearm Surgery in 159 participants. Completed in 16 April 2024.
15 April 2024
Quick facts
| Lead sponsor | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 159 |
| Start date | 3 October 2023 |
| Primary completion | 15 April 2024 |
| Estimated completion | 16 April 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Infraclavicular brachial plexus block
Conditions studied
- Forearm Surgery — all drugs for Forearm Surgery →
Sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Who can join
Adults 18 to 55, any sex, with Forearm Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Infraclavicular brachial plexus block in hand and forearm surgery has the advantages of high success rate and low risk of complications and is useful in providing long-lasting and effective postoperative analgesia in these patients. In response to hypoxemia at high altitude, increased blood viscosity, decreased carbon monoxide diffusion capacity, increased cerebral arterial blood flow, decreased blood volume and decreased cardiac output occur. At high altitude, the serum level of local anesthetics may increase due to an increase in their ionized fraction and a decrease in their clearance. In this respect, the pharmacodynamic and pharmacokinetic properties of peripheral nerve blocks may be altered when performed at high altitude. The primary objective of this prospective study was to test the hypothesis that postoperative pain scores are higher in patients undergoing infraclavicular nerve block at high altitude than in patients at low altitude. This multicenter prospective randomized study will be initiated after approval of the Ethics Committee of Health ScienceUniversity Diyarbakir Gazi Yasargil Training and Research Hospital. Patients will be recruited simultaneously in 3 hospitals, Hatay Training and Research Hospital, Hatay, Turkey (100 m above sea level);Health Science Health Science University Diyarbakir Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey (675 m above sea level) and Health Science University Van Regional and Training Research Hospital, Van, Turkey (1726 m above sea level). Infraclavicular brachial plexus blocks (coracoid approach) will be performed by administering a local anesthetic mixture of 1.5 mg/kg lidocaine 2% + 1 mg/kg bupivacaine 0.5% at the 6 o'clock position of the axillary artery under US guidance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06027918
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other trials of Infraclavicular brachial plexus block
Trials testing the same drug.
- NCT07326436 — Comparison of Sympathetic Blockade Duration in Brachial Plexus Blocks Performed by Different Methods · NA · completed
- NCT05260736 — Comparison of Costoclavicular and Paracoracoid Approaches to Infraclavicular Brachial Plexus Blocks · NA · completed
- NCT05240729 — Using Ultrasound in Infraclavicular in Upper Limb Surgeries · NA · completed
- NCT04417608 — Looking for Minimum Dose to Induce Sympathectomy in Infraclavicular Brachial Plexus Block · unknown
- NCT03631914 — Intelligent Needle Tip Tracking Using Ultrasound Imaging for Infraclavicular Brachial Plexus Blocks · NA · completed
Other recruiting trials for Forearm Surgery
Currently open trials in the same condition.
- NCT07151443 — Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block · NA · recruiting
- NCT05602636 — Analgesic Effect of Supraclavicular Block and Interscalene Analgesia Versus an Intercostobrachial Nerve Block Versus PCA · Phase 4 · recruiting
Other Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital trials
Trials by the same sponsor.
- NCT07422649 — Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke · completed
- NCT07278895 — Dural Puncture Epidural vs Standard Epidural Analgesia in Labor · NA · completed
- NCT07345039 — Infraorbital-Infratrochlear Block vs Sphenopalatine Ganglion Block for Postoperative Analgesia in Septorhinoplasty. · NA · completed
- NCT07325331 — Lullaby vs White Noise vs Silence in Pediatric MRI Sedation · NA · completed
- NCT07306507 — vNOTES vs Laparoscopic Hysterectomy: Randomized Trial on Pain and Recovery" · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06027918 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
- Last refreshed: 23 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06027918.
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