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NCT06025838
Positive Feedback vs. No-Feedback Games for Behavioral Change
NA trial testing positive feedback in Major Depressive Disorder in 171 participants. Completed in 2 March 2024.
2 March 2024
Quick facts
| Lead sponsor | Bard College |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 171 |
| Start date | 13 February 2024 |
| Primary completion | 2 March 2024 |
| Estimated completion | 2 March 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- positive feedback
Conditions studied
- Major Depressive Disorder — all drugs for Major Depressive Disorder →
- Low Mood — all drugs for Low Mood →
Sponsor
Bard College
Who can join
Adults 18 to 34, any sex, with Major Depressive Disorder or Low Mood. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
We aim to investigate here whether we can develop a reinforcement learning game which provides game-based feedback to encourage positive actions (behaviors) both inside and outside of the game. Does providing positive reward when participants make decisions which are associated with value-based actions (like those in BA) result in different game decisions? We propose that it will increase positive actions in the game. And, secondly, how does it affect short-term behavior (in one week)? We propose that it will increase pro-health activities and may reduce depressive symptoms.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06025838
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Related trials
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Currently open trials in the same condition.
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- NCT06705478 — Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disor · Phase 2 · recruiting
- NCT06749392 — An Individual-specific Synchrony Signature · NA · recruiting
- NCT07316803 — Group Intervention for Romantic Relationships in Young Adults With Severe Mental Illness · NA · recruiting
- NCT07242105 — Optimizing Brain Excitability in Depression · NA · recruiting
Other Bard College trials
Trials by the same sponsor.
- NCT05925816 — Guided Feedback in an Online Game Impacts Decision Making · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06025838 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bard College
- Last refreshed: 14 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06025838.
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