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NCT06022913
Behavioural Activation for Bipolar Depression
NA trial testing Behavioural Activation (BA) in Bipolar Depression in 10 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Reykjavik University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 10 |
| Start date | 22 November 2023 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Iceland |
Drugs / interventions tested
- Behavioural Activation (BA)
Conditions studied
- Bipolar Depression — all drugs for Bipolar Depression →
Sponsor
Reykjavik University
Who can join
18 and older, any sex, with Bipolar Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Bipolar disorder (BD) affects between 1-3% of the world's population. People with BD experience episodes of mania or hypomania and in most cases, they experience periods of depression which can cause difficulties in daily life. Psychological therapies for people experiencing depression without mania or hypomania are widely available, but there is little research into how effective these therapies are for people with BD. Behavioral activation therapy (BA) is based on behavioral theory and has been proven to be an effective treatment for unipolar depression. It helps people re-establish healthier activity patterns and sleep regulation, especially in BD for mood stabilization. BA is theoretically and clinically well matched to the treatment of bipolar depression, but there is still very little research into offering BA to people with BD. The first aim of the current research is to implement BA for people with depression in Bipolar Disorder and study if it is feasible for this patient group. The second aim is to do a pilot study on the effectiveness of the treatment for this patient group. The research will be implemented with people seeking treatment at the specialized service for bipolar disorder at Landspítali University Hospital in Iceland. The participants will receive treatment as usual and the BA will be adjunctive. At least ten people, that are currently experiencing Bipolar Depression and are willing to take part, will receive up to 20 individual therapy sessions of BA that have been adapted for Bipolar Depression (BA-BD), and will complete regular questionnaires and interviews. The study will be a replication study to validate the previous study's findings by Kim, W. et al., 2022 in another setting.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06022913
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Behavioural Activation (BA)
Trials testing the same drug.
- NCT06322420 — Behavioral Activation for Depression and Habitual Rumination · NA · recruiting
- NCT03658824 — Behavioural Activation for Bipolar Depression: A Case Series · NA · completed
Other recruiting trials for Bipolar Depression
Currently open trials in the same condition.
- NCT07266545 — RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE) · Phase 4 · recruiting
- NCT07246044 — HD-tDCS for Adolescent Bipolar Depression Targeting S1 · NA · recruiting
- NCT07121894 — Ketogenic Intervention for Bipolar Depression · NA · recruiting
- NCT07108257 — Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression · NA · recruiting
- NCT05603104 — Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First- · Phase 3 · recruiting
Other Reykjavik University trials
Trials by the same sponsor.
- NCT05555186 — The Effects of Bright Light Therapy on Adolescent's Sleep Quality and Well-being · NA · completed
- NCT04260737 — Interactive Decision Aid for Men Diagnosed With Prostate Cancer · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06022913 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Reykjavik University
- Last refreshed: 16 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06022913.
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