NCT06019182 is a clinical trial in Intellectual Disability, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

What condition does NCT06019182 study?

NCT06019182 studies Intellectual Disability, Epilepsy, Hypogonadisms, Microcephaly, Nervous System Malformations, Obesity.

Is NCT06019182 still recruiting?

NCT06019182 is currently recruiting now. Last updated 23 February 2026.

Last reviewed 2026-02-23 · How we verify

NCT06019182

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

MEHMO Natural History and Biomarkers

Recruiting now Last updated 23 February 2026

What this trial tests

trial in Intellectual Disability in 150 participants. Currently enrolling.

Timeline

23 October 2023

Primary endpoint
1 September 2053

1 September 2053

Quick facts

Lead sponsor	Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	150
Start date	23 October 2023
Primary completion	1 September 2053
Estimated completion	1 September 2053
Sites	1 location across United States

Conditions studied

Intellectual Disability — all drugs for Intellectual Disability →
Epilepsy — all drugs for Epilepsy →
Hypogonadisms — all drugs for Hypogonadisms →
Microcephaly — all drugs for Microcephaly →

Sponsor

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Who can join

Adults 1 Week to 100, any sex, with Intellectual Disability or Epilepsy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This observational natural history study will follow individuals with MEHMO (Mental disability, Epileptic seizure, Hypopituitarism/Hypogenitalism, Microcephaly, Obesity) syndrome or an eIF2-pathway related disorder, who have symptoms such as intellectual delay, seizures, abnormal hormone and blood sugar levels, and decreased motor skills. No current treatment for these conditions is available. A major impediment to the testing of potential therapeutic interventions is the lack of well-defined outcome measures. This protocol seeks to identify biochemical and clinical markers to monitor disease progression, and better understand the natural history of these conditions. Any person diagnosed with MEHMO syndrome or related conditions, who can travel to the NIH Clinical Center can participate in this study. The study involves: * General health assessment and evaluation * Imaging studies * Laboratory tests * Collection of blood, urine, spinal fluid, skin biopsy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Intellectual Disability

Currently open trials in the same condition.

NCT05473429 — Characterization of Nociception Phenotype in Individuals With Intellectual Disability · NA · recruiting
NCT07497035 — Equine Therapy Programme on Stress, Autonomy and Balance in School-age Children With Intellectual Disabilities · NA · active not recruiting
NCT07059858 — Bladder and Bowel Functions, Participation and Quality of Life in Children With Intellectual Disabilities · recruiting
NCT07278544 — Harnessing Communication Preferences · NA · recruiting
NCT06829264 — Testing an Evidence-Based Supported Employment Model in Autistic Young Adults · NA · recruiting

Other Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) trials

Trials by the same sponsor.

NCT07502586 — Turner Syndrome: Genetic Considerations · recruiting
NCT07357701 — Identifying Genome Variants in Non-Obstructive Azoospermia (NOA) or Primary Ovarian Insufficiency (POI) · recruiting
NCT06851754 — Hormone Replacement Therapy in Adolescents With Premature Ovarian Insufficiency · Phase 3 · recruiting
NCT05548881 — Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnan · withdrawn
NCT06749366 — Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06019182 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Last refreshed: 23 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06019182.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing