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NCT06015971

Omega-3 Fatty Acids and Nutritional Support in Gastrointestinal Cancer

Recruiting now NA Last updated 6 May 2025
What this trial tests

NA trial testing omega-3 in Sarcopenia in 40 participants. Currently enrolling.

Timeline
1 July 2023
Primary endpoint
31 December 2026
31 December 2026

Quick facts

Lead sponsorMaimónides Biomedical Research Institute of Córdoba
PhaseNA
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposesupportive care
Enrollment40
Start date1 July 2023
Primary completion31 December 2026
Estimated completion31 December 2026
Sites1 location across Spain

Drugs / interventions tested

Conditions studied

Sponsor

Maimónides Biomedical Research Institute of Córdoba

Who can join

18 and older, any sex, with Sarcopenia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Sarcopenia is a frequent complication in patients with cancer and chronic diseases, it is characterized by decreased muscle strength and fatigue due to reduced skeletal muscle mass, which is accompanied by atrophy and decreased quality of muscle tissue. In all cases, it negatively impacts treatment tolerance, clinical outcomes and survival, in consequence, quality of life of these patients decreases while morbidity, mortality and costs increase. In this context, appropriate nutritional screening and early nutrition support are extremely recommended, to this aim, in some cases, oral nutritional supplements (ONS) are necessary; ONS could have a standard formula or be enriched with specific nutrients (arginine, glutamine, branched chain amino acids, n-3 fatty acids, and nucleotides), which can modulate the activity of the immune system and provide an additional benefit beyond the nutritional support, this intervention type is called immunonutrition. Despite these possible benefits, their utility has been proven in few clinical scenarios, for example in with patients with upper gastrointestinal cancer undergoing surgical resection; based on this, current guidelines recommend that patients should receive oral/enteral nutritional support with an specific formula enriched in immunonutrients (with arginine, n-3 fatty acids or nucleotides) , but there is a lack of evidence for supporting its use in other clinical conditions including patients with cancer that receive systemic treatment

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other trials of omega-3

Trials testing the same drug.

Other recruiting trials for Sarcopenia

Currently open trials in the same condition.

Other Maimónides Biomedical Research Institute of Córdoba trials

Trials by the same sponsor.

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Data sources for this page

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