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NCT06007274: TILT
Troponin to Detect Major Cardiovasculaire Advserse Events on Immune Checkpoint Inhibitors
trial testing No intervention in Cancer in 300 participants. Completed in 1 July 2024.
1 April 2024
Quick facts
| Lead sponsor | Institut Mutualiste Montsouris |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 1 July 2023 |
| Primary completion | 1 April 2024 |
| Estimated completion | 1 July 2024 |
| Sites | 1 location across France |
Drugs / interventions tested
- No intervention
Conditions studied
- Cancer — all drugs for Cancer →
- Immune Checkpoint Inhibitor — all drugs for Immune Checkpoint Inhibitor →
- Cardiovascular Biomarkers — all drugs for Cardiovascular Biomarkers →
Sponsor
Institut Mutualiste Montsouris — full company profile →
Who can join
18 and older, any sex, with Cancer or Immune Checkpoint Inhibitor. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recent guidelines suggest the use of troponin to detect immnune related cardiovascular advserse events in patients treated by immune checkpoint inhibitors for cancer. However, there is no proof that patients on immune checkpoint inhibitors benefit from this active surveillance strategy. The suspicion of cardiovascular events may lead to the interruption of cancer therapies. The TILT study aims at assessing: (i) the efficiency of troponin measurments in asymptomatic patients to prevent the further advent of major cardiovascular events; (ii) its safety in terms of cancer therapy completion.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06007274
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06007274 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Institut Mutualiste Montsouris
- Last refreshed: 8 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06007274.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing