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NCT05999318
pBFS-guided cTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
NA trial testing active continuous Theta Burst Stimulation in Stroke, Ischemic in 40 participants. Currently enrolling.
20 August 2025
Quick facts
| Lead sponsor | Changping Laboratory |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 7 November 2023 |
| Primary completion | 20 August 2025 |
| Estimated completion | 20 August 2026 |
| Sites | 2 locations across China |
Drugs / interventions tested
- active continuous Theta Burst Stimulation
- sham continuous Theta Burst Stimulation
Conditions studied
- Stroke, Ischemic — all drugs for Stroke, Ischemic →
- Aphasia — all drugs for Aphasia →
Sponsor
Changping Laboratory
Who can join
Adults 35 to 75, any sex, with Stroke, Ischemic or Aphasia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this trial is to evaluate the effectiveness and safeness of continuous Theta Burst Stimulation (cTBS) over the right Superior Temporal Gyrus (STG), guided by personalized Brain Function Sector (pBFS) technology, on language function recovery in patients with post-ischemic stroke aphasia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05999318
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of active continuous Theta Burst Stimulation
Trials testing the same drug.
- NCT05907031 — pBFS-guided cTBS Over the Inferior Frontal Gyrus for Aphasia After Ischemic Stroke · NA · recruiting
- NCT05957445 — pBFS-guided Multi-target cTBS for Aphasia After Stroke · NA · recruiting
- NCT05957354 — pBFS-guided Dual-target cTBS for Aphasia After Stroke · NA · recruiting
Other recruiting trials for Stroke, Ischemic
Currently open trials in the same condition.
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- NCT07135089 — Improving Neuroprotective Strategy for Ischemic Stroke Before Endovascular Thrombectomy by Intravenous Tirofiban · Phase 3 · recruiting
- NCT07047014 — Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ische · Phase 3 · recruiting
Other Changping Laboratory trials
Trials by the same sponsor.
- NCT06350396 — pBFS-guided rTMS Over DMPFC for Treatment-Resistant Depression · NA · recruiting
- NCT06255535 — pBFS Guided rTMS Over Cognitive Control Network for ASD · NA · recruiting
- NCT06255561 — pBFS Guided rTMS Over Different Targets for Treatment-Resistant Depression · NA · unknown
- NCT06166082 — Stanford Neuromodulation Therapy (SNT) for the Treatment-Resistant Depression · NA · unknown
- NCT06112652 — Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05999318 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Changping Laboratory
- Last refreshed: 4 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05999318.
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