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pBFS Guided rTMS Over Different Targets for Treatment-Resistant Depression
To explore the effectiveness and safety of rTMS intervention with different targets in the left prefrontal cortex defined using the pBFS method, in adult patients with moderate and severe depressive disorder. Second, investigate the neural circuit that responds to the rTMS intervention using individualized brain image analysis, which may help to establish an effective target for the neuromodulation of patients with major depressive disorder.
Details
| Lead sponsor | Changping Laboratory |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 75 |
| Start date | Tue Feb 20 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Thu Jan 30 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Major Depressive Disorder
- Treatment Resistant Depression
- MDD
Interventions
- active rTMS stimulating