Last reviewed · How we verify
NCT05991141
Could Apnea Induce Hypoalgesia?
NA trial testing Apnea in Pain in 30 participants. Completed in 15 May 2023.
15 May 2023
Quick facts
| Lead sponsor | Centro Universitario La Salle |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 1 February 2023 |
| Primary completion | 15 May 2023 |
| Estimated completion | 15 May 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Apnea
- Control Intervention — full drug profile →
Conditions studied
Sponsor
Centro Universitario La Salle
Who can join
Adults 18 to 30, any sex, with Pain or Apnea. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized controlled trial (RCT) in healthy subjects will be conducted with the following aims: (1) Explore the effect of low pulmonary volume dynamic apnoea bouts on Pressure Pain Threshold (PPT) and conditioned pain modulation (CPM); (2) analyse whether CPM response correlates with apnoea induced hypoalgesia; (3) examine the association between apnoea bouts, Rate of Perceived Exertion, hypoxemia and Heart Rate changes in PPT.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of Apnea-Induced Hypoxia on Hypoalgesia in Healthy Subjects.
Mendoza-Arranz C, López-Rebenaque O, Cabrera-López CD, López-Mejías A, et al · · 2024 · cited 1× · PMID 39590896 · DOI 10.3390/sports12110294
Verify or expand the search:
- PubMed search for NCT05991141
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Apnea
Trials testing the same drug.
- NCT05302219 — Plethysmography Curve Variability Depending on the Breath Cycle · NA · completed
- NCT04290728 — High-flow Nasal Oxygenation for Open Mouth · NA · terminated
Other recruiting trials for Pain
Currently open trials in the same condition.
- NCT07533409 — Tactile and Pain Sensory Thresholds and Hand Grip Strength · recruiting
- NCT07294092 — Ketamine and Propofol NeuroImaging · EARLY_PHASE1 · recruiting
- NCT07290205 — Remimazolam NeuroImaging · EARLY_PHASE1 · recruiting
- NCT07487610 — Relationship Between Neuropathic Pain and Geriatric Assessment Parameters in Patients Aged 80 Years and Older · recruiting
- NCT07454993 — The Effect of Music During Colonoscopy · NA · recruiting
Other Centro Universitario La Salle trials
Trials by the same sponsor.
- NCT07427979 — Sex Differences in Exercise-Induced Hypoalgesia · NA · not yet recruiting
- NCT06765486 — Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions · NA · recruiting
- NCT06283186 — Comparative Exercise-Induced Hypoalgesia in Upper and Lower Limbs: A Randomized Controlled Trial in Healthy Individuals · Phase 1 · recruiting
- NCT06150677 — Effects of Static Apnea at High Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function · Phase 3 · unknown
- NCT06158256 — Effects of Static Apnea at Low Lung Volume on Hypoalgesia, Cardiovascular Function and Respiratory Function · Phase 3 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05991141 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centro Universitario La Salle
- Last refreshed: 14 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05991141.
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