NCT05985629 is a Phase 4 clinical trial of IPACK in Pain, Postoperative, sponsored by Loyola University.

Who is sponsoring NCT05985629?

NCT05985629 is sponsored by Loyola University.

What drugs are being tested in NCT05985629?

Interventions in NCT05985629: IPACK, PLACEBO.

What condition does NCT05985629 study?

NCT05985629 studies Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid.

Is NCT05985629 still recruiting?

NCT05985629 is currently recruiting now. Last updated 14 August 2023.

Last reviewed 2023-08-14 · How we verify

NCT05985629

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

IPACK on Early Pain Scores After ACL Reconstruction

Recruiting now Phase 4 Last updated 14 August 2023

What this trial tests

Phase 4 trial testing IPACK in Pain, Postoperative in 78 participants. Currently enrolling.

Timeline

3 August 2023

Primary endpoint
3 August 2025

3 August 2026

Quick facts

Lead sponsor	Loyola University
Phase	Phase 4
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	78
Start date	3 August 2023
Primary completion	3 August 2025
Estimated completion	3 August 2026
Sites	1 location across United States

Drugs / interventions tested

IPACK — full drug profile →
PLACEBO

Conditions studied

Pain, Postoperative — all drugs for Pain, Postoperative →
Anterior Cruciate Ligament Injuries — all drugs for Anterior Cruciate Ligament Injuries →
Analgesics, Opioid — all drugs for Analgesics, Opioid →

Sponsor

Loyola University

Who can join

16 and older, any sex, with Pain, Postoperative or Anterior Cruciate Ligament Injuries. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery. The main questions it aims to answer are: * if participants who receive the IPACK block prior to ACL reconstruction experience less pain after surgery and at 1 day after surgery * if participants who receive the IPACK block prior to ACL reconstruction require less short-term opioid use immediately after surgery and up to one week after surgery. Participants will be randomized 1:1 to 1 of 2 groups: Use of IPACK block during ACL reconstruction vs. placebo (a placebo is a look-alike substance that contains no active drug). Neither the participant nor the investigator will know which group the participants has been assigned to. Researchers will compare self-reported pain scores and short-term opioid use of all study participants.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of IPACK

Trials testing the same drug.

NCT06712394 — Knee Osteoarthritis and IPACK · not yet recruiting
NCT05303233 — IPACK or Selective Tibial Nerve Block for ACL Reconstruction With an Adductor Canal Block · NA · completed
NCT04499716 — Quadriblock Versus "IPACK + Femoral Triangle Block + Obturator Nerve Block" in Total Knee Arthroplasty · NA · completed
NCT04213287 — Multimodal Analgesia Methods in Patients Undergoing IPACK Block in Knee Arthroplasty · NA · unknown

Other recruiting trials for Pain, Postoperative

Currently open trials in the same condition.

NCT07512141 — Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy · NA · recruiting
NCT07354581 — Erector Spinae Plane Block vs Quadro-Iliac Plane Block After Lumbar Instrumentation Surgery · NA · recruiting
NCT07239817 — PENG Block + LIA For Endoprosthesis Surgery With Anterior Approach · NA · recruiting
NCT06740214 — Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty · Phase 3 · recruiting
NCT07057557 — Aloe Vera vs Paraffin Tulle Dressings for Pain Management in Split Thickness Skin Graft Donor Sites · NA · recruiting

Other Loyola University trials

Trials by the same sponsor.

NCT07517224 — Assessing the Effect of an Aerobic Exercise Program on Vascular Function in Women With Non-Metastatic Breast Cancer · NA · not yet recruiting
NCT06486714 — Mechanical Alignment Versus Kinematic Alignment Total Knee Arthroplasty · NA · not yet recruiting
NCT07216664 — Multisensory Early Oral Administration of Human Milk (M-MILK) for Very Preterm Infants · NA · recruiting
NCT07226505 — Effects of Core Strengthening Exercises for Treating TMD · NA · not yet recruiting
NCT06525701 — Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05985629 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Loyola University
Last refreshed: 14 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05985629.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing