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NCT05981469: CASPAR

Can Cervical Stiffness Predict Successful Vaginal Delivery After Induction of Labour?

Completed Last updated 22 April 2025
What this trial tests

trial testing Cervical Stiffness Assessmenr in Induced Vaginal Delivery in 100 participants. Completed in 29 November 2024.

Timeline
29 September 2023
Primary endpoint
29 November 2024
29 November 2024

Quick facts

Lead sponsorUniversity of Liverpool
StatusCompleted
Study typeOBSERVATIONAL
Enrollment100
Start date29 September 2023
Primary completion29 November 2024
Estimated completion29 November 2024
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Liverpool

Who can join

Adults 18 to 50, female only, with Induced Vaginal Delivery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine if a new antenatal test of cervical stiffness can be used to predict which patients will have a successful vaginal delivery following an induction of labour. A licensed, CE-marked, vacuum-aspiration device called the Pregnolia system has been developed to give quantitative cervical stiffness index score during pregnancy. The CASPAR study will compare cervical stiffness scores to bishop's scores prior to induction of labour and correlate the results to the outcome of delivery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? a feasibility, cohort study.
    Medford E, Lane S, Merriel A, Sharp A, et al · · 2025 · cited 1× · PMID 39820788 · DOI 10.1371/journal.pone.0311324
  2. Study Protocol. The CASPAR study protocol. Can cervical stiffness predict successful vaginal delivery after induction of labour? A feasibility, cohort study
    Medford E, Lane S, Merriel A, Sharp A, et al · · 2024 · DOI 10.1101/2024.09.19.24314025

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Other University of Liverpool trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05981469.

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