NCT05970094 (REMA-CKD) is a NA clinical trial of Low PRAL in Kidney Diseases, sponsored by University of Copenhagen.

Who is sponsoring NCT05970094?

NCT05970094 is sponsored by University of Copenhagen.

What drugs are being tested in NCT05970094?

Interventions in NCT05970094: Low PRAL.

What condition does NCT05970094 study?

NCT05970094 studies Kidney Diseases, Metabolic Acidosis, Renal Insufficiency, CKD, Pre-dialysis.

Is NCT05970094 still recruiting?

NCT05970094 is currently completed. Last updated 4 December 2023.

Last reviewed 2023-12-04 · How we verify

NCT05970094: REMA-CKD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5

Completed NA Last updated 4 December 2023

What this trial tests

NA trial testing Low PRAL in Kidney Diseases in 20 participants. Completed in 20 November 2023.

Timeline

6 March 2023

Primary endpoint
20 August 2023

20 November 2023

Quick facts

Lead sponsor	University of Copenhagen
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	20
Start date	6 March 2023
Primary completion	20 August 2023
Estimated completion	20 November 2023
Sites	1 location across Denmark

Drugs / interventions tested

Low PRAL

Conditions studied

Kidney Diseases — all drugs for Kidney Diseases →
Metabolic Acidosis — all drugs for Metabolic Acidosis →
Renal Insufficiency — all drugs for Renal Insufficiency →
CKD — all drugs for CKD →

Sponsor

University of Copenhagen

Who can join

18 and older, any sex, with Kidney Diseases or Metabolic Acidosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to learn about and test the effect of an acid/base diet, in chronic kidney patients with CKD stage 4 and 5 in an interventional study with a historical control. The hypothesize is, that an acid/base diet will reduce the degree of acidosis and the need for oral bicarbonate supplements.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Dietary acid load in health and disease.
Wieërs MLAJ, Beynon-Cobb B, Visser WJ, Attaye I. · · 2024 · cited 28× · PMID 38282081 · DOI 10.1007/s00424-024-02910-7

Verify or expand the search:

Other trials of Low PRAL

Trials testing the same drug.

NCT05784389 — Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 · NA · unknown

Other recruiting trials for Kidney Diseases

Currently open trials in the same condition.

NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting
NCT07217535 — Rutgers University Study of the Genetics of Kidney Disease · recruiting
NCT06858319 — Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. · Phase 3 · recruiting
NCT06798909 — Kidney Transplant Preemptive Therapy or Prophylaxis for CMV Prevention in D+R Recipients · Phase 3 · recruiting
NCT06759077 — Cardio Protective Effect of SGL2I in Hemodialysis Patients and Its Impact on Patient Quality of Life · Phase 3 · active not recruiting

Other University of Copenhagen trials

Trials by the same sponsor.

NCT07461324 — Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI · not yet recruiting
NCT07389421 — School Meals in Denmark · NA · not yet recruiting
NCT07450690 — Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy · NA · recruiting
NCT07302880 — The Acute Interference of Biotin in Blood Analysis · NA · not yet recruiting
NCT07312981 — The CPH-MBD Cohort Dietary Substudy - Comparison of Methods for Dietary Registrations · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05970094 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Copenhagen
Last refreshed: 4 December 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05970094.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing