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NCT05969548
pBFS-guided cTBS at Different Doses for Aphasia After Stroke
NA trial testing active 1200-pulse continuous Theta Burst Stimulation in Stroke in 60 participants. Currently enrolling.
22 September 2025
Quick facts
| Lead sponsor | Changping Laboratory |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 22 September 2023 |
| Primary completion | 22 September 2025 |
| Estimated completion | 22 December 2025 |
| Sites | 2 locations across China |
Drugs / interventions tested
- active 1200-pulse continuous Theta Burst Stimulation
- active 2400-pulse continuous Theta Burst Stimulation
- active 3600-pulse continuous Theta Burst Stimulation
- sham 1200-pulse continuous Theta Burst Stimulation
- sham 2400-pulse continuous Theta Burst Stimulation
- sham 3600-pulse continuous Theta Burst Stimulation
Conditions studied
Sponsor
Changping Laboratory
Who can join
Adults 35 to 75, any sex, with Stroke or Aphasia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this trial is to evaluate the effectiveness and safeness of different doses of continuous Theta Burst Stimulation (cTBS) over the right Superior Frontal Gyrus (SFG), guided by personalized Brain Function Sector (pBFS) technology, on language function recovery in patients with post-stroke aphasia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05969548
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Changping Laboratory trials
Trials by the same sponsor.
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- NCT06255535 — pBFS Guided rTMS Over Cognitive Control Network for ASD · NA · recruiting
- NCT06255561 — pBFS Guided rTMS Over Different Targets for Treatment-Resistant Depression · NA · unknown
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- NCT06112652 — Neuromodulation of Different Doses to Treat TRD Guided by pBFS Technique · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05969548 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Changping Laboratory
- Last refreshed: 4 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05969548.
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