NCT05962203: MV-FIT

SHIP-AGE: Frailty, Renal Function, and Multi-component Primary Care in Rural Mecklenburg-Western Pomerania

Not yet recruiting NA Last updated 27 July 2023

What this trial tests

NA trial testing Multi-factorial geriatric assessment, monitoring & management systems in Frailty Syndrome in 820 participants. Not yet recruiting.

Timeline

1 September 2023

Primary endpoint
30 June 2028

31 December 2029

Quick facts

Lead sponsor	University Medicine Greifswald
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	prevention
Enrollment	820
Start date	1 September 2023
Primary completion	30 June 2028
Estimated completion	31 December 2029

Drugs / interventions tested

• Multi-factorial geriatric assessment, monitoring & management systems

Conditions studied

• Frailty Syndrome — all drugs for Frailty Syndrome →

Sponsor

University Medicine Greifswald

Who can join

Adults 65 to 100, any sex, with Frailty Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Chronic kidney disease (CKD) is a leading risk factor for cardiovascular and all-cause mortality among the elderly. Mecklenburg-Western Pomerania has the largest prevalence of CKD in Germany and Europe. The CKD impact in primary care strategies to reduce frailty syndrome in the elderly is unknown. For this purpose, about 820 elderly participants will be included in an observational study (MV-FIT), who will undergo an multi-factorial geriatric assessment, monitoring \& management program, specifically designed to avoid frailty. The goal of the full-scale study is to evaluate the impact of CKD in multi-component primary care strategies to reduce frailty among elderly persons in rural Mecklenburg-Western Pomerania. MV-FIT will be conducted on individuals in rural Mecklenburg-Western Pomerania, who will be observed over a period of 3 years. The Study of Health in Pomerania (SHIP) is a population-based epidemiological, two independent-cohort, study (SHIP and SHIP-TREND). SHIP cohorts have been followed for \>24 years. SHIP/SHIP TEND participants \>60 years or older will studied by a follow-up survey. The aim is to gain new insights into the development of frailty and to develop strategies for keeping those affected healthy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol.
   Gollasch M, Komleva Y, Tsvetkov D, Morof F, et al · · 2025 · PMID 40489434 · DOI 10.1371/journal.pone.0324001