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NCT05952349
Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.
Phase 2 trial testing OLIVE OIL 5ML/5MG (BD) NUTRITIONAL SACHET 2100MG (BD) in PCO in 88 participants. Completed in 1 April 2024.
31 December 2023
Quick facts
| Lead sponsor | Khyber Medical University Peshawar |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 88 |
| Start date | 1 July 2023 |
| Primary completion | 31 December 2023 |
| Estimated completion | 1 April 2024 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- OLIVE OIL 5ML/5MG (BD) NUTRITIONAL SACHET 2100MG (BD) — full drug profile →
- Metformin (1000 mg Twice a day) — full drug profile →
Conditions studied
- PCO — all drugs for PCO →
Sponsor
Khyber Medical University Peshawar
Who can join
Adults 18 to 34, female only, with PCO. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators aim is to conduct randomized clinical trial, to determine the effects of metformin and combination of olive oil plus nutritional supplements on inflammatory markers IL-8 and IL6 in polycystic ovarian syndrome (PCOS). Women diagnosed with PCOS using "Rotterdam diagnostic criteria" according to which two out of three characters must be their in women of PCOS. The investigators propose that PCOS women have increase levels of IL-6 ,IL-8 and this therapy would have beneficial effects and is able to reduce their increase interleukins levels .
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05952349
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for PCO
Currently open trials in the same condition.
- NCT06302166 — Effects of HICT and Intermittent Fasting on PCOS · NA · recruiting
Other Khyber Medical University Peshawar trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05952349 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Khyber Medical University Peshawar
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05952349.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing