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NCT05950607: TRAIN-AD 2
Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
NA trial testing TRAIN AD 2.0 in Dementia in 750 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | Hebrew SeniorLife |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | health services research |
| Enrollment | 750 |
| Start date | 13 November 2023 |
| Primary completion | 30 June 2026 |
| Estimated completion | 30 June 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- TRAIN AD 2.0
Conditions studied
- Dementia — all drugs for Dementia →
- Alzheimer Disease — all drugs for Alzheimer Disease →
- Infections — all drugs for Infections →
Sponsor
Hebrew SeniorLife — full company profile →
Who can join
Adults 60 to 106, any sex, with Dementia or Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main questions it aims to answer whether residents with dementia in nursing homes randomized to use a multicomponent intervention to optimize suspected infection management ( versus usual care) use less antibiotics and fewer burdensome interventions.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05950607
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dementia
Currently open trials in the same condition.
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- NCT06088810 — The Impact of Music Intervention on Sleep · NA · recruiting
- NCT07482800 — Dementia in Fiction and Clinical Narratives · recruiting
- NCT07392944 — Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Home · NA · recruiting
Other Hebrew SeniorLife trials
Trials by the same sponsor.
- NCT06771531 — Brain Stimulation for Foot-sole Sensation in Older Adults With Foot-sole Somatosensory Deficits · NA · recruiting
- NCT06770400 — Sleep Improvement Via Environmental Smart Temperature Adjustments · NA · active not recruiting
- NCT06008431 — Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait) · NA · completed
- NCT05937165 — ABSORB (Amount of Blueberries So Older Adults Reap Benefits) · NA · completed
- NCT05906446 — Post-acute Multicomponent Frailty Intervention · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05950607 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hebrew SeniorLife
- Last refreshed: 6 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05950607.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing