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NCT05936944: iWOnDer
Role of Natural Light in the Prevention of Delirium After Cardiac Surgery: a Prospective Observational Study With Historical Control
trial testing Exposure to totally artificial lighting in Intensive Care Unit Delirium in 448 participants. Completed in 22 June 2024.
22 June 2024
Quick facts
| Lead sponsor | Azienda Ospedaliero-Universitaria di Parma |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 448 |
| Start date | 14 June 2023 |
| Primary completion | 22 June 2024 |
| Estimated completion | 22 June 2024 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Exposure to totally artificial lighting
Conditions studied
- Intensive Care Unit Delirium — all drugs for Intensive Care Unit Delirium →
- Postoperative Delirium — all drugs for Postoperative Delirium →
- Cardiac Surgery — all drugs for Cardiac Surgery →
Sponsor
Azienda Ospedaliero-Universitaria di Parma — full company profile →
Who can join
18 and older, any sex, with Intensive Care Unit Delirium or Postoperative Delirium. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Postoperative delirium is a common complication that usually occurs acutely within the first 24 hours after surgery and resolves within 72 hours; it is common in all medical areas and particularly affects patients over the age of 65 and those with pre-existing cognitive impairments. It is characterized by difficulty organizing and coordinating thoughts and by slowing down motor functions that are observed for a short period after surgery. The study will be an observational prospective study with historical control (pre/post-study) whose primary objective is to identify the incidence of postoperative delirium in patients undergoing cardiac surgery. The population will be adult patients undergoing cardiac surgery at our University Hospital over a period of 12 months. The intervention will be exposure to totally artificial light (for patients hospitalized after the relocation of the department to its original location). The comparator will be exposure to natural light (for patients who will be hospitalized during our temporary transfer to an environment with natural lighting). The outcome will be the incidence of delirium, measured with the Confusion Assessment Method-Intensive Care Unit (CAM-ICU) scale; episodes of agitation requiring sedative drugs; time elapsed before onset of delirium. The study will last 12 months.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05936944
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Intensive Care Unit Delirium
Currently open trials in the same condition.
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- NCT05467410 — Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors · NA · active not recruiting
- NCT06172491 — Automating Delirium Severity in the ICU · recruiting
Other Azienda Ospedaliero-Universitaria di Parma trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05936944 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Azienda Ospedaliero-Universitaria di Parma
- Last refreshed: 2 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05936944.
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