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NCT05930626
Biomarkers of Acrylamide, Glycidol, POPs, PFAS and Disease Outcomes and OMICs Signatures
trial testing Biomarkers of acrylamide, glycidol, POPs, PFAS in Disease in 9,254 participants. Completed in 31 December 2008.
31 December 2008
Quick facts
| Lead sponsor | Karolinska Institutet |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 9,254 |
| Start date | 1 January 1997 |
| Primary completion | 31 December 2008 |
| Estimated completion | 31 December 2008 |
Drugs / interventions tested
- Biomarkers of acrylamide, glycidol, POPs, PFAS
Conditions studied
- Disease — all drugs for Disease →
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
- Cancer — all drugs for Cancer →
- Environmental Exposure — all drugs for Environmental Exposure →
Sponsor
Karolinska Institutet
Who can join
Eligibility, any sex, with Disease or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the project is to assess the associations between biomarkers of acrylamide and glycidol exposure and disease outcomes in a case-cohort study based on two prospective cohorts with biobanks. The investigators also aim to assess the exposure-affected OMICS signatures and molecular pathways underlying disease development (specifically cardiovascular diseases such as myocardial infarction and stroke and cancer such as breast-, endometrial and colorectal cancer) for these exposures along with persistent organic pollutants (POPs) and per- and polyflouroalkyl substances (PFAS) using a prospective cohort study utilizing and integrating various 'OMICs' technologies.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
OMICs Signatures Linking Persistent Organic Pollutants to Cardiovascular Disease in the Swedish Mammography Cohort.
Schillemans T, Yan Y, Ribbenstedt A, Donat-Vargas C, et al · · 2024 · cited 11× · PMID 38174696 · DOI 10.1021/acs.est.3c06388
Verify or expand the search:
- PubMed search for NCT05930626
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05930626 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska Institutet
- Last refreshed: 5 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05930626.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing