Last reviewed · How we verify

NCT05930626

Biomarkers of Acrylamide, Glycidol, POPs, PFAS and Disease Outcomes and OMICs Signatures

Completed Last updated 5 July 2023
What this trial tests

trial testing Biomarkers of acrylamide, glycidol, POPs, PFAS in Disease in 9,254 participants. Completed in 31 December 2008.

Timeline
1 January 1997
Primary endpoint
31 December 2008
31 December 2008

Quick facts

Lead sponsorKarolinska Institutet
StatusCompleted
Study typeOBSERVATIONAL
Enrollment9,254
Start date1 January 1997
Primary completion31 December 2008
Estimated completion31 December 2008

Drugs / interventions tested

Conditions studied

Sponsor

Karolinska Institutet

Who can join

Eligibility, any sex, with Disease or Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the project is to assess the associations between biomarkers of acrylamide and glycidol exposure and disease outcomes in a case-cohort study based on two prospective cohorts with biobanks. The investigators also aim to assess the exposure-affected OMICS signatures and molecular pathways underlying disease development (specifically cardiovascular diseases such as myocardial infarction and stroke and cancer such as breast-, endometrial and colorectal cancer) for these exposures along with persistent organic pollutants (POPs) and per- and polyflouroalkyl substances (PFAS) using a prospective cohort study utilizing and integrating various 'OMICs' technologies.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. OMICs Signatures Linking Persistent Organic Pollutants to Cardiovascular Disease in the Swedish Mammography Cohort.
    Schillemans T, Yan Y, Ribbenstedt A, Donat-Vargas C, et al · · 2024 · cited 11× · PMID 38174696 · DOI 10.1021/acs.est.3c06388

Verify or expand the search:

Other recruiting trials for Disease

Currently open trials in the same condition.

Other Karolinska Institutet trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05930626.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing