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NCT05917067: FLUOPATCH

Fluorescence Imaging of the Parathyroid Glands of Children

Completed Last updated 30 January 2025
What this trial tests

trial testing Fluorescence imaging of the parathyroid glands of children in Childhood Thyroid Gland Carcinoma in 23 participants. Completed in 1 December 2024.

Timeline
1 September 2023
Primary endpoint
1 October 2024
1 December 2024

Quick facts

Lead sponsorAmsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)
StatusCompleted
Study typeOBSERVATIONAL
Enrollment23
Start date1 September 2023
Primary completion1 October 2024
Estimated completion1 December 2024
Sites3 locations across Netherlands

Drugs / interventions tested

Conditions studied

Sponsor

Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)

Who can join

Under 18, any sex, with Childhood Thyroid Gland Carcinoma or Thyroid Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to develop a standardized and user-independent imaging workflow model for autofluorescence and quantified fluorescence angiography with Indocyanine Green (ICG) of the parathyroid glands of children. For this purpose, all pediatric patients will undergo thyroid surgery with the use of autofluorescence and quantified ICG-fluorescence. This study could be the first step in reducing the rate of postoperative hypocalcemia in children, by using fluorescence angiography during pediatric thyroid surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Quantified Fluorescence Imaging for the Detection and Perfusion of the Parathyroid Glands of Children (FLUOPATCH): Study Protocol for a Proof-of-Concept Study
    de Berg DJv, Kruijff S, Trotsenburg APv, Santen HMv, et al · · 2024 · DOI 10.21203/rs.3.rs-4840337/v1

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